(D68.4) Acquired coagulation factor deficiency

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734 830 in individuals diagnosis acquired coagulation factor deficiency confirmed
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26 707 deaths with diagnosis acquired coagulation factor deficiency
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4% mortality rate associated with the disease acquired coagulation factor deficiency

Diagnosis acquired coagulation factor deficiency is diagnosed Women are 9.01% more likely than Men

334 299

Men receive the diagnosis acquired coagulation factor deficiency

11 162 (3.3 %)

Died from this diagnosis.

100
95
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400 531

Women receive the diagnosis acquired coagulation factor deficiency

15 545 (3.9 %)

Died from this diagnosis.

Risk Group for the Disease acquired coagulation factor deficiency - Men aged 75-79 and Women aged 80-84

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In Men diagnosis is most often set at age 0-95+
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in in men, the disease manifests at any agein in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features acquired coagulation factor deficiency

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Absence or low individual and public risk
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Acquired coagulation factor deficiency - what does this mean

Acquired coagulation factor deficiency is a disorder in which the body does not produce enough of the proteins (clotting factors) that are necessary for normal blood clotting. this can lead to excessive bleeding or a tendency to form abnormal blood clots. the cause of this disorder can be due to certain medications, liver disease, vitamin k deficiency, or other medical conditions.

What happens during the disease - acquired coagulation factor deficiency

Acquired coagulation factor deficiency is caused by a decrease in the production of specific coagulation factors in the body. this can be due to a variety of underlying causes, such as liver disease, vitamin k deficiency, or certain medications. the deficiency of these factors can lead to an increased risk of bleeding, which can cause serious health complications.

Clinical Pattern

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How does a doctor diagnose

  • Complete blood count (CBC)
  • Coagulation studies (PT, aPTT, INR)
  • Fibrinogen level
  • Factor VIII and IX levels
  • Factor V levels
  • D-dimer levels
  • Antiphospholipid antibody testing
  • Antithrombin III levels
  • Protein C and S levels
  • Genetic testing

Treatment and Medical Assistance

Main goal of the treatment: To restore the patient's coagulation factor levels to normal.
  • Administering factor replacement therapy
  • Prescribing anticoagulants to reduce the risk of blood clots
  • Providing nutritional support to maintain a balanced diet
  • Monitoring of laboratory tests to evaluate the effectiveness of the treatment
  • Encouraging the patient to get adequate rest and exercise
  • Educating the patient about the disease and its management
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14 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Acquired coagulation factor deficiency - Prevention

Prevention of acquired coagulation factor deficiency involves avoiding exposure to toxins, such as certain medications, alcohol, and environmental pollutants, that can interfere with the body's ability to produce coagulation factors. additionally, it is important to maintain a healthy lifestyle by eating a balanced diet, exercising regularly, and getting adequate rest. vaccinations, such as those for hepatitis a and b, can also help prevent acquired coagulation factor deficiency.