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(G72.0) Drug-induced myopathy
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349 096 in individuals diagnosis drug-induced myopathy confirmed
8 471 deaths with diagnosis drug-induced myopathy
2% mortality rate associated with the disease drug-induced myopathy
Diagnosis drug-induced myopathy is diagnosed Men are 5.94% more likely than Women
184 919
Men receive the diagnosis drug-induced myopathy
4 309 (2.3 %)Died from this diagnosis.
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164 177
Women receive the diagnosis drug-induced myopathy
4 162 (2.5 %)Died from this diagnosis.
Risk Group for the Disease drug-induced myopathy - Men aged 60-64 and Women aged 80-84
In Men diagnosis is most often set at age 0-94
Less common in men the disease occurs at Age 95+in in women, the disease manifests at any age
In Women diagnosis is most often set at age 0-95+
Disease Features drug-induced myopathy
Absence or low individual and public risk
Drug-induced myopathy - what does this mean
Drug-induced myopathy is a type of muscle disorder caused by the use of certain medications. it is characterized by muscle weakness, pain and tenderness, and can be caused by medications such as statins, glucocorticoids, and anti-convulsants.
What happens during the disease - drug-induced myopathy
Drug-induced myopathy is a type of muscle disorder caused by the use of certain medications, such as statins, antiretrovirals, and corticosteroids. it is thought to be caused by the drugs' interference with normal muscle metabolism, leading to the accumulation of toxic metabolites, disruption of calcium homeostasis, and mitochondrial damage. this can lead to muscle weakness and pain, as well as other symptoms.
Clinical Pattern
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How does a doctor diagnose
- Perform a physical examination of the patient to identify any muscular weakness or tenderness.
- Order laboratory tests such as serum creatine kinase (CK) and aldolase levels to measure the level of muscle damage.
- Request an electromyography (EMG) to assess the electrical activity of the muscles.
- Conduct a biopsy of the affected muscle to check for evidence of inflammation or damage.
- Order a muscle imaging test such as magnetic resonance imaging (MRI) to look for any structural abnormalities.
- Conduct a comprehensive drug history of the patient to identify any drugs that may be causing the myopathy.
Treatment and Medical Assistance
Main goal of the treatment: Reduce symptoms of Drug-induced myopathy and improve overall health.
- Prescribe medications to reduce inflammation and muscle pain.
- Perform physical therapy exercises to improve muscle strength and range of motion.
- Provide dietary advice to improve nutrition and reduce inflammation.
- Recommend lifestyle changes to reduce stress and improve overall health.
- Refer patient to specialists for further evaluation and treatment.
- Monitor patient’s progress and adjust treatment plan accordingly.
21 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Drug-induced myopathy - Prevention
Drug-induced myopathy can be prevented by avoiding the use of drugs that are known to cause this condition, such as statins, corticosteroids, and antiretroviral drugs. additionally, patients should be monitored closely for any signs of muscle weakness or pain while taking these medications, and the dosage should be adjusted accordingly.