(G72.3) Periodic paralysis

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349 096 in individuals diagnosis periodic paralysis confirmed
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8 471 deaths with diagnosis periodic paralysis
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2% mortality rate associated with the disease periodic paralysis

Diagnosis periodic paralysis is diagnosed Men are 5.94% more likely than Women

184 919

Men receive the diagnosis periodic paralysis

4 309 (2.3 %)

Died from this diagnosis.

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95
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164 177

Women receive the diagnosis periodic paralysis

4 162 (2.5 %)

Died from this diagnosis.

Risk Group for the Disease periodic paralysis - Men aged 60-64 and Women aged 80-84

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In Men diagnosis is most often set at age 0-94
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Less common in men the disease occurs at Age 95+in in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features periodic paralysis

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Absence or low individual and public risk
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Periodic paralysis - what does this mean

Periodic paralysis is a rare genetic disorder characterized by episodes of muscle weakness that can last from minutes to days. it is caused by mutations in genes that encode ion channels, leading to abnormal levels of sodium, calcium, and potassium that interfere with muscle contraction.

What happens during the disease - periodic paralysis

Periodic paralysis is a rare genetic disorder caused by mutations in genes related to ion channels, which are responsible for controlling the flow of sodium and potassium ions in and out of muscle cells. these mutations can cause the ion channels to malfunction, leading to a disruption of the normal balance of ions in the muscle cells. this can cause the muscles to become weak or paralyzed, especially during periods of rest or high potassium levels. this can lead to episodes of paralysis that can last for minutes or hours.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Physical examination
  • Electromyography (EMG)
  • Blood tests
  • Urine tests
  • X-ray
  • CT scan
  • Electrocardiogram (ECG)
  • Muscle biopsy
  • Genetic testing

Treatment and Medical Assistance

Main Goal of the Treatment: To reduce the frequency and severity of symptoms of Periodic Paralysis.
  • Prescribing medications to reduce the severity of muscle weakness
  • Administering potassium or glucose intravenously to reduce the severity of an attack
  • Prescribing medications to reduce the frequency of attacks
  • Encouraging the patient to maintain a healthy lifestyle by exercising regularly and eating a balanced diet
  • Providing counseling to help the patient cope with the psychological impact of the disease
  • Referring the patient to a physical therapist to help with muscle weakness
  • Referring the patient to a nutritionist to help with dietary modifications
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21 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Periodic paralysis - Prevention

Periodic paralysis is a rare genetic disorder that can be prevented by avoiding triggers such as stress, strenuous activity, certain medications, and high-carbohydrate meals. eating a balanced diet, getting regular exercise, and avoiding triggers can help to reduce the risk of developing periodic paralysis.