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(L43.2) Lichenoid drug reaction
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176 205 in individuals diagnosis lichenoid drug reaction confirmed
Diagnosis lichenoid drug reaction is diagnosed Women are 36.75% more likely than Men
55 726
Men receive the diagnosis lichenoid drug reaction
0 (less than 0.1%)Died from this diagnosis.
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120 479
Women receive the diagnosis lichenoid drug reaction
0 (less than 0.1%)Died from this diagnosis.
Risk Group for the Disease lichenoid drug reaction - Men and Women aged 55-59
In Men diagnosis is most often set at age 5-89, 95+
Less common in men the disease occurs at Age 0-5, 90-94Less common in women the disease occurs at Age 0-5, 10-14, 95+
In Women diagnosis is most often set at age 5-9, 15-94
Disease Features lichenoid drug reaction
Absence or low individual and public risk
Lichenoid drug reaction - what does this mean
Lichenoid drug reaction is an immune-mediated inflammatory skin reaction that occurs in response to certain medications. it is characterized by the presence of small, itchy, and scaly patches that may be red or purple in color, and is often localized to areas that are exposed to the drug.
What happens during the disease - lichenoid drug reaction
Lichenoid drug reaction is a type of immune-mediated hypersensitivity reaction caused by the use of certain medications. it is thought to be caused by a combination of direct drug toxicity and a type iv delayed-type hypersensitivity reaction to the drug. the drug-specific immune response leads to the formation of a lichenoid inflammatory infiltrate composed of lymphocytes, histiocytes, and occasional eosinophils in the skin, which leads to the characteristic rash.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete medical history and physical examination
- Laboratory tests including complete blood count, liver and kidney function tests, and urinalysis
- Skin biopsy
- Patch testing (to identify the allergen responsible for the reaction)
- Phototesting (to identify the allergen responsible for the reaction)
- Patch testing (to identify the allergen responsible for the reaction)
- Skin prick testing (to identify the allergen responsible for the reaction)
- Immunofluorescence (to identify the antibodies responsible for the reaction)
Treatment and Medical Assistance
Main Goal: Treat Lichenoid Drug Reaction
- Monitor the patient's drug intake
- Conduct skin biopsy to confirm diagnosis
- Discontinue the drug that is causing the reaction
- Prescribe topical corticosteroids to reduce inflammation
- Prescribe oral corticosteroids to reduce inflammation
- Prescribe oral antihistamines to reduce itching
- Prescribe topical calcineurin inhibitors to reduce inflammation
- Prescribe systemic immunosuppressants to reduce inflammation
- Prescribe phototherapy to reduce inflammation
- Prescribe topical retinoids to reduce inflammation
- Prescribe systemic retinoids to reduce inflammation
- Prescribe topical antibiotics to reduce infection
- Prescribe systemic antibiotics to reduce infection
14 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Lichenoid drug reaction - Prevention
Lichenoid drug reaction can be prevented by avoiding the use of drugs known to cause the reaction, such as nonsteroidal anti-inflammatory drugs, penicillins, and sulfonamides. it is also important to monitor for signs and symptoms of the reaction, and to seek prompt medical attention if any are observed.