DocSym
β
Searchsearch
Search
(L62.0*) Clubbed nail pachydermoperiostosis
More details coming soon
NaN% mortality rate associated with the disease clubbed nail pachydermoperiostosis
Diagnosis clubbed nail pachydermoperiostosis is diagnosed Prevalent in Women Only
0
Men receive the diagnosis clubbed nail pachydermoperiostosis
0 (No mortality)Died from this diagnosis.
100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
0
Women receive the diagnosis clubbed nail pachydermoperiostosis
0 (No mortality)Died from this diagnosis.
Risk Group for the Disease clubbed nail pachydermoperiostosis - Men and Women aged 0
No Cases of the Disease Clubbed nail pachydermoperiostosis identified in Men
Less common in men the disease occurs at Age 0-95+Less common in women the disease occurs at Age 0-95+
No Cases of the Disease Clubbed nail pachydermoperiostosis identified in Men
Disease Features clubbed nail pachydermoperiostosis
Absence or low individual and public risk
Clubbed nail pachydermoperiostosis - what does this mean
Clubbed nail pachydermoperiostosis is a rare disorder caused by the mutation of the hpgd gene. it is characterized by clubbing of the fingers and toes, thickening of the skin, and enlargement of the bones, leading to joint pain and stiffness.
What happens during the disease - clubbed nail pachydermoperiostosis
Clubbed nail pachydermoperiostosis is a rare, autosomal dominant disorder caused by mutations in the slco2a1 gene. the disorder is characterized by clubbing of the nails, thickening of the skin, and periosteal new bone formation. the exact pathogenesis of the disorder is unknown, but it is believed to be caused by abnormal production of prostaglandins, which can lead to changes in the nail matrix and thickening of the skin. these changes can also lead to periosteal new bone formation, which is a hallmark of the disorder.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete physical examination
- Laboratory tests including complete blood count, erythrocyte sedimentation rate, and C-reactive protein
- Radiographic imaging of the affected area
- Biopsy of the affected area
- Genetic testing
- Pulmonary function tests
- Cardiac evaluation
Treatment and Medical Assistance
Main goal of the treatment: To reduce pain and improve the function of the affected area.
- Medication to reduce inflammation and pain
- Physical therapy to improve joint mobility
- Occupational therapy to improve hand function
- Surgery to remove the affected tissue
- Cold packs to reduce swelling
- Corticosteroid injections to reduce inflammation
- Splinting to protect the affected area
No Hospitalization Required
Average Time for Outpatient Care Not Established
Clubbed nail pachydermoperiostosis - Prevention
Clubbed nail pachydermoperiostosis is a rare genetic disorder, so prevention is not possible. however, early diagnosis and treatment of the condition can help to reduce the severity of symptoms and improve the long-term prognosis.