(M34.1) Cr(e)st syndrome

More details coming soon

589 161 in individuals diagnosis cr(e)st syndrome confirmed

30 703 deaths with diagnosis cr(e)st syndrome

5% mortality rate associated with the disease cr(e)st syndrome

Etiology Pathogenesis Clinical Pattern Diagnostics Treatment Prevention

Diagnosis cr(e)st syndrome is diagnosed Women are 60.53% more likely than Men

116 268

Men receive the diagnosis cr(e)st syndrome

8 382 (7.2 %)

Died from this diagnosis.

100

472 893

Women receive the diagnosis cr(e)st syndrome

22 321 (4.7 %)

Died from this diagnosis.

Risk Group for the Disease cr(e)st syndrome - Men aged 50-54 and Women aged 55-59

In Men diagnosis is most often set at age 5-89

Less common in men the disease occurs at Age 0-5, 90-95+Less common in women the disease occurs at Age 0-1, 90-95+

In Women diagnosis is most often set at age 0-89

Disease Features cr(e)st syndrome

Absence or low individual and public risk

Cr(e)st syndrome - what does this mean

Cr(e)st syndrome is an autoimmune disorder that occurs when a person's immune system mistakenly attacks their own connective tissue, leading to the formation of antibodies that cause inflammation, pain, and damage to the skin, joints, and other organs. symptoms of the disorder can include rashes, joint pain, and raynaud's phenomenon.

What happens during the disease - cr(e)st syndrome

Cr(e)st syndrome is a rare autoimmune disorder caused by the production of autoantibodies that attack the connective tissue of the skin, leading to the formation of fibrous bands in the skin and underlying tissues. this results in a variety of symptoms including skin thickening, scarring, and joint contractures. additionally, it can lead to systemic inflammatory and immune problems such as vasculitis and organ damage.

Clinical Pattern

More details coming soon

How does a doctor diagnose

Physical exam
Blood tests
X-rays
CT scans
MRI scans
Ultrasound exams
Electrocardiogram (ECG)
Echocardiogram (ECHO)
Cardiac catheterization

Treatment and Medical Assistance

Main goal of the treatment: To reduce symptoms and improve quality of life for individuals with CR(E)ST syndrome

Developing a treatment plan tailored to individual needs
Managing medications to reduce inflammation
Providing physical and occupational therapy
Encouraging lifestyle changes, such as regular exercise and stress reduction
Using assistive devices, such as braces and splints, to improve mobility
Providing counseling and support for mental health issues
Educating patients and families about the disease and its management

13 Days of Hospitalization Required

Average Time for Outpatient Care Not Established

Cr(e)st syndrome - Prevention

Cr(e)st syndrome prevention involves avoiding environmental triggers such as smoking, dust, and chemical exposure, as well as maintaining a healthy lifestyle with regular exercise and a balanced diet. additionally, it is important to get regular check-ups with a doctor to monitor for any early signs of the condition.

Diseases with similar symptoms