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(M34) Systemic sclerosis
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589 161 in individuals diagnosis systemic sclerosis confirmed
30 703 deaths with diagnosis systemic sclerosis
5% mortality rate associated with the disease systemic sclerosis
Diagnosis systemic sclerosis is diagnosed Women are 60.53% more likely than Men
116 268
Men receive the diagnosis systemic sclerosis
8 382 (7.2 %)Died from this diagnosis.
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472 893
Women receive the diagnosis systemic sclerosis
22 321 (4.7 %)Died from this diagnosis.
Risk Group for the Disease systemic sclerosis - Men aged 50-54 and Women aged 55-59
In Men diagnosis is most often set at age 5-89
Less common in men the disease occurs at Age 0-5, 90-95+Less common in women the disease occurs at Age 0-1, 90-95+
In Women diagnosis is most often set at age 0-89
Disease Features systemic sclerosis
Absence or low individual and public risk
Systemic sclerosis - what does this mean
Systemic sclerosis is a chronic autoimmune disorder that affects the connective tissue of the body. it is characterized by an overproduction of collagen, leading to thickening of the skin and fibrosis of internal organs, including the heart, lungs, and gastrointestinal tract. this thickening and fibrosis can lead to decreased organ function and decreased blood flow, resulting in a variety of symptoms, including fatigue, joint pain, and difficulty breathing.
What happens during the disease - systemic sclerosis
Systemic sclerosis is a chronic autoimmune disease characterized by widespread tissue fibrosis and vascular abnormalities. it is caused by dysregulated immune responses leading to the release of pro-inflammatory cytokines, which activate fibroblasts and promote excessive deposition of extracellular matrix components. this leads to increased vascular resistance, tissue fibrosis, and organ dysfunction. additionally, autoantibodies may be produced which further contribute to the pathogenesis of systemic sclerosis.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete physical examination
- Blood tests to check for anemia, kidney function, and inflammation
- X-ray or CT scan of the chest to check for lung involvement
- Electrocardiogram (ECG) to check for heart involvement
- Ultrasound to check for liver or spleen involvement
- Skin biopsy to check for thickening of the skin
- Pulmonary function tests to check for lung involvement
- MRI or CT scan of the head to check for brain involvement
- Magnetic resonance angiography (MRA) to check for blood vessel involvement
Treatment and Medical Assistance
Main goal of the treatment: To reduce the progression of the disease and improve the patient's quality of life.
- Early diagnosis and treatment of any underlying conditions that may be causing or contributing to systemic sclerosis.
- Medications to reduce inflammation and control the immune system.
- Physical therapy to improve mobility, strength, and flexibility.
- Occupational therapy to help with everyday tasks.
- Psychological counseling to help with emotional issues.
- Nutritional counseling to help with dietary modifications.
- Breathing exercises to help with breathing difficulties.
- Stress management to help with fatigue and other symptoms.
- Support groups to help with coping with the disease.
13 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Systemic sclerosis - Prevention
Systemic sclerosis can be prevented by avoiding exposure to environmental toxins, reducing stress levels, maintaining a healthy diet, and exercising regularly. additionally, it is important to seek prompt medical attention for any signs or symptoms of the condition, such as raynaud's phenomenon, joint pain, and skin thickening.