Porphyria cutanea tarda - what does this mean
Porphyria cutanea tarda (pct) is a rare metabolic disorder caused by a deficiency of the enzyme uroporphyrinogen decarboxylase, resulting in an accumulation of porphyrins in the skin and other organs. this leads to photosensitivity, skin fragility, and blistering, as well as liver disease.
What happens during the disease - porphyria cutanea tarda
Porphyria cutanea tarda (pct) is caused by a genetic deficiency of the enzyme uroporphyrinogen decarboxylase (urod). this deficiency leads to the accumulation of porphyrins and their precursors in the body, which can cause photosensitivity, liver disease, and other symptoms. this accumulation is thought to be caused by a combination of environmental factors, such as alcohol consumption, smoking, and iron overload, as well as genetic factors, such as mutations in the urod gene.
Porphyria cutanea tarda - Prevention
Porphyria cutanea tarda can be prevented by avoiding alcohol, maintaining a healthy diet, avoiding smoking, and reducing exposure to environmental toxins such as pesticides. additionally, avoiding iron supplements and certain medications can also help to reduce the risk of developing this condition.