(N02.6) Recurrent and persistent haematuria : dense deposit disease

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415 686 in individuals diagnosis recurrent and persistent haematuria : dense deposit disease confirmed
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3 757 deaths with diagnosis recurrent and persistent haematuria : dense deposit disease
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1% mortality rate associated with the disease recurrent and persistent haematuria : dense deposit disease

Diagnosis recurrent and persistent haematuria : dense deposit disease is diagnosed Men are 20.32% more likely than Women

250 077

Men receive the diagnosis recurrent and persistent haematuria : dense deposit disease

2 465 (1.0 %)

Died from this diagnosis.

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165 609

Women receive the diagnosis recurrent and persistent haematuria : dense deposit disease

1 292 (0.8 %)

Died from this diagnosis.

Risk Group for the Disease recurrent and persistent haematuria : dense deposit disease - Men aged 75-79 and Women aged 10-14

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In Men diagnosis is most often set at age 0-95+
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in in men, the disease manifests at any agein in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features recurrent and persistent haematuria : dense deposit disease

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Absence or low individual and public risk
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Recurrent and persistent haematuria : dense deposit disease - what does this mean

Recurrent and persistent haematuria due to dense deposit disease is caused by a mutation in the cfh gene which results in the formation of abnormal deposits in the glomerular basement membrane of the kidney causing inflammation and damage to the kidney cells resulting in haematuria.

What happens during the disease - recurrent and persistent haematuria : dense deposit disease

Recurrent and persistent haematuria due to dense deposit disease is caused by a dysfunction in the alternative complement pathway, which leads to the formation of dense deposits in the glomerular basement membrane. this results in a decrease in the glomerular filtration rate, leading to the presence of red blood cells in the urine. in addition, the deposition of dense deposits in the glomerular basement membrane can cause inflammation and scarring of the glomeruli, leading to further disruption of the filtration process and the presence of red blood cells in the urine.

Clinical Pattern

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How does a doctor diagnose

  • Urine analysis
  • Kidney biopsy
  • Imaging tests such as ultrasound, CT scan, MRI
  • Blood tests to check kidney function
  • Urine culture to check for infection
  • Genetic testing for mutations associated with DDD

Treatment and Medical Assistance

Main goal of the treatment: To reduce the frequency and severity of recurrent and persistent haematuria due to dense deposit disease.
  • Administer anti-inflammatory medications such as corticosteroids.
  • Prescribe immunosuppressive medications.
  • Monitor the patient’s urine for signs of infection.
  • Encourage the patient to drink plenty of fluids.
  • Provide lifestyle advice to reduce the risk of recurrence.
  • Provide psychological support to help the patient cope with the condition.
  • Refer the patient to a specialist if necessary.
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9 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Recurrent and persistent haematuria : dense deposit disease - Prevention

The best way to prevent recurrent and persistent haematuria due to dense deposit disease is to maintain a healthy lifestyle, including regular exercise, a balanced diet, and avoiding smoking and excessive alcohol consumption. in addition, if a person has a family history of the condition, they should be monitored closely for any signs of the disease.