(N04.1) Nephrotic syndrome : focal and segmental glomerular lesions

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1 288 076 in individuals diagnosis nephrotic syndrome : focal and segmental glomerular lesions confirmed

9 412 deaths with diagnosis nephrotic syndrome : focal and segmental glomerular lesions

1% mortality rate associated with the disease nephrotic syndrome : focal and segmental glomerular lesions

Etiology Pathogenesis Clinical Pattern Diagnostics Treatment Prevention

Diagnosis nephrotic syndrome : focal and segmental glomerular lesions is diagnosed Men are 19.20% more likely than Women

767 701

Men receive the diagnosis nephrotic syndrome : focal and segmental glomerular lesions

4 730 (0.6 %)

Died from this diagnosis.

100

520 375

Women receive the diagnosis nephrotic syndrome : focal and segmental glomerular lesions

4 682 (0.9 %)

Died from this diagnosis.

Risk Group for the Disease nephrotic syndrome : focal and segmental glomerular lesions - Men and Women aged 5-9

In Men diagnosis is most often set at age 0-94

Less common in men the disease occurs at Age 95+Less common in women the disease occurs at Age 95+

In Women diagnosis is most often set at age 0-94

Disease Features nephrotic syndrome : focal and segmental glomerular lesions

Absence or low individual and public risk

Nephrotic syndrome : focal and segmental glomerular lesions - what does this mean

Nephrotic syndrome is caused by focal and segmental glomerular lesions, which are abnormalities in the filtering units of the kidney (glomeruli). these lesions cause the kidney to leak large amounts of protein into the urine, leading to a decrease in the amount of protein in the bloodstream. this can cause fluid to build up in the body, leading to swelling, high cholesterol, and an increased risk of infection.

What happens during the disease - nephrotic syndrome : focal and segmental glomerular lesions

Nephrotic syndrome is caused by focal and segmental glomerular lesions in the kidneys. these lesions cause damage to the glomerular basement membrane, resulting in increased permeability of proteins and other substances. this leads to proteinuria, hypoalbuminemia, edema, and hyperlipidemia, which are the hallmark symptoms of nephrotic syndrome.

Clinical Pattern

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How does a doctor diagnose

Complete physical examination
Urinalysis
Blood tests including complete blood count, serum creatinine, electrolytes, and uric acid
Kidney biopsy
Imaging tests such as ultrasound, CT scan, and MRI
Renal function tests such as glomerular filtration rate and serum albumin
Urine protein test
Urine sediment analysis
Kidney tissue examination

Treatment and Medical Assistance

Main goal of the Treatment: Reduce proteinuria and prevent complications.

Prescribe steroids and other immunosuppressants to reduce inflammation.
Prescribe medications to reduce the amount of proteins lost in urine.
Provide dietary advice to reduce the amount of salt and protein intake.
Monitor for signs of infection and treat any infections promptly.
Monitor for signs of high blood pressure and treat accordingly.
Monitor for signs of fluid retention and treat accordingly.
Monitor for signs of kidney damage and treat accordingly.
Monitor for signs of anemia and treat accordingly.

14 Days of Hospitalization Required

Average Time for Outpatient Care Not Established

Nephrotic syndrome : focal and segmental glomerular lesions - Prevention

Nephrotic syndrome can be prevented by maintaining a healthy lifestyle, including eating a balanced diet, exercising regularly, and avoiding smoking and excessive alcohol consumption. additionally, controlling high blood pressure and cholesterol levels, managing diabetes, and taking prescribed medications as directed can also help to reduce the risk of developing focal and segmental glomerular lesions.

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