(N04.3) Nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis

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1 288 076 in individuals diagnosis nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis confirmed
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9 412 deaths with diagnosis nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis
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1% mortality rate associated with the disease nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis

Diagnosis nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis is diagnosed Men are 19.20% more likely than Women

767 701

Men receive the diagnosis nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis

4 730 (0.6 %)

Died from this diagnosis.

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520 375

Women receive the diagnosis nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis

4 682 (0.9 %)

Died from this diagnosis.

Risk Group for the Disease nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis - Men and Women aged 5-9

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In Men diagnosis is most often set at age 0-94
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Less common in men the disease occurs at Age 95+Less common in women the disease occurs at Age 95+
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In Women diagnosis is most often set at age 0-94

Disease Features nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis

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Absence or low individual and public risk
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Nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis - what does this mean

Nephrotic syndrome is caused by diffuse mesangial proliferative glomerulonephritis, which is a type of glomerulonephritis that is characterized by an inflammation of the glomeruli (the tiny blood vessels in the kidneys) that leads to an increase in the number of mesangial cells and an increase in the size of the glomeruli. this can lead to an increased permeability of the glomerular filtration barrier, resulting in proteinuria (protein in the urine) and edema (swelling).

What happens during the disease - nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis

Nephrotic syndrome is caused by diffuse mesangial proliferative glomerulonephritis, an immune-mediated disorder that results in inflammation and thickening of the basement membrane in the glomeruli. this results in increased permeability of the glomerular basement membrane, allowing for the leakage of proteins, such as albumin, into the urine. this proteinuria, along with edema and hypoalbuminemia, are the hallmark symptoms of nephrotic syndrome.

Clinical Pattern

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How does a doctor diagnose

  • Complete physical examination
  • Urine analysis
  • Blood tests (including creatinine, BUN, and electrolytes)
  • Kidney biopsy
  • Imaging tests (such as ultrasound, CT scan, or MRI)
  • Renal function tests (such as glomerular filtration rate)
Additions:
  • Urinalysis to check for proteinuria (excessive protein in the urine)

Treatment and Medical Assistance

Main goal: Control the symptoms and prevent further damage to the kidneys.
  • Prescribe corticosteroids and other immunosuppressive agents to reduce inflammation and suppress the immune system.
  • Prescribe diuretics to reduce fluid retention and reduce the workload on the kidneys.
  • Prescribe ACE inhibitors and angiotensin receptor blockers to reduce blood pressure and protect the kidneys from further damage.
  • Prescribe medications to reduce cholesterol levels and reduce the risk of further kidney damage.
  • Prescribe iron supplements to treat anemia.
  • Prescribe anticoagulants to reduce the risk of blood clots.
  • Prescribe antibiotics to treat any infections.
  • Monitor blood pressure, urine output, and other laboratory tests regularly.
  • Encourage the patient to exercise and maintain a healthy diet.
  • Provide education and support to the patient and their family.
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14 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis - Prevention

Nephrotic syndrome is best prevented through early detection and treatment of diffuse mesangial proliferative glomerulonephritis. this includes regular monitoring of kidney function, controlling blood pressure, avoiding drugs that can damage the kidneys, and maintaining a healthy lifestyle with a balanced diet and regular exercise. if the condition is detected early, prompt treatment can reduce the risk of complications and long-term damage to the kidneys.