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(D80.7) Transient hypogammaglobulinaemia of infancy
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230 829 in individuals diagnosis transient hypogammaglobulinaemia of infancy confirmed
3 237 deaths with diagnosis transient hypogammaglobulinaemia of infancy
1% mortality rate associated with the disease transient hypogammaglobulinaemia of infancy
Diagnosis transient hypogammaglobulinaemia of infancy is diagnosed Men are 29.67% more likely than Women
149 656
Men receive the diagnosis transient hypogammaglobulinaemia of infancy
1 396 (0.9 %)Died from this diagnosis.
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Women receive the diagnosis transient hypogammaglobulinaemia of infancy
1 841 (2.3 %)Died from this diagnosis.
Risk Group for the Disease transient hypogammaglobulinaemia of infancy - Men and Women aged 0-5
In Men diagnosis is most often set at age 0-89
Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 35-39, 85-95+
In Women diagnosis is most often set at age 0-34, 40-84
Disease Features transient hypogammaglobulinaemia of infancy
Absence or low individual and public risk
Transient hypogammaglobulinaemia of infancy - what does this mean
Transient hypogammaglobulinaemia of infancy is a disorder of the immune system in which the body does not produce enough gamma globulins, which are proteins that help fight infections. this can lead to recurrent infections, especially of the respiratory tract, and can occur in infants up to two years of age.
What happens during the disease - transient hypogammaglobulinaemia of infancy
Transient hypogammaglobulinaemia of infancy is caused by an immature immune system, which is unable to produce enough immunoglobulins to protect the infant from infections. this is due to a lack of maturation of b-lymphocytes, which are responsible for producing immunoglobulins. this results in the infant being more susceptible to infections, and can cause a decrease in the amount of immunoglobulins in the blood.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete blood count (CBC)
- Serum protein electrophoresis (SPEP)
- Immunoglobulin levels in serum
- Immunoglobulin G (IgG) subclass levels
- Quantitative immunoglobulins
- Flow cytometry
- Antibody titers
- T-cell subsets
- B-cell subsets
- Bone marrow biopsy
- Genetic testing
Treatment and Medical Assistance
Main goal of the treatment: To restore normal levels of immunoglobulins
- Perform a thorough physical examination to assess the patient's overall health and determine the cause of the condition
- Conduct laboratory tests to measure immunoglobulin levels and diagnose the condition
- Prescribe antibiotics to treat any underlying infections
- Administer intravenous immunoglobulin (IVIG) therapy to replace low levels of immunoglobulins
- Monitor the patient's response to treatment and adjust the dosage of IVIG as needed
- Provide lifestyle advice to help the patient manage their condition
- Refer the patient to a specialist for further evaluation and treatment, if necessary
7 Days of Hospitalization Required
126 Hours Required for Outpatient Treatment
Transient hypogammaglobulinaemia of infancy - Prevention
Transient hypogammaglobulinaemia of infancy can be prevented by ensuring that infants receive regular vaccinations, breastfeeding for at least 6 months, and avoiding exposure to any potential environmental hazards. additionally, regular check-ups with a pediatrician are important to ensure that the infant is developing normally and to detect any signs of the condition early.