(P55.0) Rh isoimmunization of fetus and newborn

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747 925 in individuals diagnosis rh isoimmunization of fetus and newborn confirmed

1 731 deaths with diagnosis rh isoimmunization of fetus and newborn

Etiology Pathogenesis Clinical Pattern Diagnostics Treatment Prevention

Diagnosis rh isoimmunization of fetus and newborn is diagnosed Women are 3.07% more likely than Men

362 484

Men receive the diagnosis rh isoimmunization of fetus and newborn

660 (0.2 %)

Died from this diagnosis.

100

385 441

Women receive the diagnosis rh isoimmunization of fetus and newborn

1 071 (0.3 %)

Died from this diagnosis.

Risk Group for the Disease rh isoimmunization of fetus and newborn - Men and Women aged 0

In Men diagnosis is most often set at age 0-5

Less common in men the disease occurs at Age 5-95+Less common in women the disease occurs at Age 0-95+

In Women diagnosis is most often set at age 0-1

Disease Features rh isoimmunization of fetus and newborn

Absence or low individual and public risk

Rh isoimmunization of fetus and newborn - what does this mean

Rh isoimmunization of fetus and newborn occurs when a pregnant woman who is rh-negative is exposed to rh-positive fetal blood cells, causing her body to produce antibodies against the rh-positive cells. these antibodies can cross the placenta and attack the fetus's red blood cells, causing a condition known as hemolytic disease of the fetus and newborn.

What happens during the disease - rh isoimmunization of fetus and newborn

Rh isoimmunization of fetus and newborn is caused by maternal sensitization to the rh factor, which is an antigen found on red blood cells. when a woman with rh negative blood is exposed to rh positive blood, either through a transfusion or through pregnancy, her body produces antibodies to the rh factor. these antibodies can cross the placenta and attack the fetus's rh positive red blood cells, leading to anemia, jaundice, and other health problems in the newborn.

Clinical Pattern

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How does a doctor diagnose

Review of maternal history
A complete physical examination of the mother
Ultrasound examination of the fetus
Maternal serum screening tests
Fetal blood sampling
Amniocentesis
Rh typing of the mother and fetus
Cordocentesis
Fetal echocardiography
Genetic studies
Newborn screening tests
Treatment of Rh isoimmunization of fetus and newborn

Treatment and Medical Assistance

Main goal of the treatment: To prevent Rh isoimmunization of fetus and newborn.

Administer Rh immune globulin (Rhogam) to Rh-negative pregnant women.
Administer Rh immune globulin (Rhogam) to Rh-negative women after miscarriages, ectopic pregnancies, induced abortions, and amniocentesis.
Administer Rh immune globulin (Rhogam) to Rh-negative women with a history of prior Rh isoimmunization.
Administer Rh immune globulin (Rhogam) to Rh-negative women who have had a delivery of an Rh-positive baby.
Administer Rh immune globulin (Rhogam) to Rh-negative women who have had a transfusion of Rh-positive blood.
Administer Rh immune globulin (Rhogam) to Rh-negative women who have had a positive Rh antibody test.
Administer Rh immune globulin (Rhogam) to Rh-negative newborns.
Administer Rh immune globulin (Rhogam) to Rh-positive newborns whose mothers are Rh-negative.
Administer Rh immune globulin (Rhogam) to Rh-positive newborns whose mothers are Rh-positive and have had a history of prior Rh isoimmunization.
Administer Rh immune globulin (Rhogam) to Rh-positive newborns whose mothers are Rh-positive and have had a delivery of an Rh-positive baby.
Administer Rh immune globulin (Rhogam) to Rh-positive newborns whose mothers are Rh-positive and have had a transfusion of Rh-positive blood.
Administer Rh immune globulin (Rhogam) to Rh-positive newborns whose mothers are Rh-positive and have had a positive Rh antibody test.
Monitor the Rh status of the fetus and newborn.
Monitor the Rh status of the mother.
Perform Rh-typing of the newborn.
Perform Rh-typing of the mother.
Perform Rh-typing of the father.
Perform Rh-typing of the donor.
Perform Rh-typing of the fetus.
Perform Rh-typing of the cord blood.
Perform Rh-typing of the placenta.
Perform Rh-typing of the amniotic fluid.
Perform Rh-typing of the maternal serum.
Perform Rh-typing of the fetal serum.
Perform Rh-typing of the maternal cells.
Perform Rh-typing of the fetal cells.
Perform Rh-typing of the maternal red blood cells.
Perform Rh-typing of the fetal red blood cells.
Perform Rh-typing of the maternal white blood cells.
Perform Rh-typing of the fetal white blood cells.
Perform Rh-typing of the maternal platelets.
Perform Rh-typing of the fetal platelets.
Perform Rh-typing of the maternal plasma.
Perform Rh-typing of the fetal plasma.

11 Days of Hospitalization Required

Average Time for Outpatient Care Not Established

Rh isoimmunization of fetus and newborn - Prevention

Rh isoimmunization of the fetus and newborn can be prevented through the administration of rh immune globulin to rh-negative mothers during pregnancy, typically between 28 and 30 weeks, and after delivery or termination of pregnancy. this helps to prevent the mother's immune system from developing antibodies to the rh factor, which can be passed to the fetus or newborn, leading to rh isoimmunization.

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