(P56.0) Hydrops fetalis due to isoimmunization

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2 250 in individuals diagnosis hydrops fetalis due to isoimmunization confirmed
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2 297 deaths with diagnosis hydrops fetalis due to isoimmunization
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102% mortality rate associated with the disease hydrops fetalis due to isoimmunization

Diagnosis hydrops fetalis due to isoimmunization is diagnosed Men are 31.73% more likely than Women

1 482

Men receive the diagnosis hydrops fetalis due to isoimmunization

1 957 (132.1 %)

Died from this diagnosis.

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768

Women receive the diagnosis hydrops fetalis due to isoimmunization

340 (44.3 %)

Died from this diagnosis.

Risk Group for the Disease hydrops fetalis due to isoimmunization - Men and Women aged 0

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In Men diagnosis is most often set at age 0-1
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Less common in men the disease occurs at Age 0-95+Less common in women the disease occurs at Age 0-95+
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In Women diagnosis is most often set at age 0-1

Disease Features hydrops fetalis due to isoimmunization

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Absence or low individual and public risk
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Hydrops fetalis due to isoimmunization - what does this mean

Hydrops fetalis due to isoimmunization is a condition in which a mother's antibodies cross the placenta and attack fetal red blood cells, causing anemia and a buildup of fluid in the fetus. this can lead to severe complications, including heart failure, organ damage, and even death.

What happens during the disease - hydrops fetalis due to isoimmunization

Hydrops fetalis due to isoimmunization is caused by an antibody-mediated reaction in which maternal antibodies cross the placenta and bind to fetal red blood cells. this triggers an immune system response, leading to hemolysis and destruction of fetal red blood cells. this results in anemia and the accumulation of fluid in the fetal tissues, leading to the development of hydrops fetalis.

Clinical Pattern

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How does a doctor diagnose

  • Complete physical examination
  • Complete blood count
  • Ultrasound of the fetus
  • Amniocentesis to check for Rh isoimmunization
  • Tests to check for infections
  • Fetal echocardiogram to assess the heart
  • Fetal MRI to assess the brain
  • Fetal Doppler ultrasound to assess blood flow

Treatment and Medical Assistance

Main goal of the treatment: To reduce the risk of complications and improve the prognosis of hydrops fetalis due to isoimmunization.
  • Administer Rh immunoglobulin to the mother.
  • Monitor the fetus for any signs of anemia.
  • Administer intrauterine transfusions to the fetus if needed.
  • Monitor the fetus for hydrops.
  • Monitor the mother for any signs of preterm labor.
  • Monitor the mother for any signs of infection.
  • Administer antibiotics to the mother if needed.
  • Monitor the fetus for any signs of infection.
  • Administer steroids to the mother if needed.
  • Perform an amniocentesis to assess the fetal lung maturity.
  • Perform an ultrasound to assess the fetal heart rate.
  • Perform an ultrasound to assess the fetal growth.
  • Perform an ultrasound to assess the fetal fluid levels.
  • Deliver the fetus at the appropriate gestational age.
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21 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Hydrops fetalis due to isoimmunization - Prevention

Hydrops fetalis due to isoimmunization can be prevented by administering rhogam to rh-negative mothers during pregnancy and immediately following birth, as well as testing for rh incompatibility between mother and fetus and treating accordingly.