(P56) Hydrops fetalis due to haemolytic disease

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2 250 in individuals diagnosis hydrops fetalis due to haemolytic disease confirmed
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2 297 deaths with diagnosis hydrops fetalis due to haemolytic disease
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102% mortality rate associated with the disease hydrops fetalis due to haemolytic disease

Diagnosis hydrops fetalis due to haemolytic disease is diagnosed Men are 31.73% more likely than Women

1 482

Men receive the diagnosis hydrops fetalis due to haemolytic disease

1 957 (132.1 %)

Died from this diagnosis.

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Women receive the diagnosis hydrops fetalis due to haemolytic disease

340 (44.3 %)

Died from this diagnosis.

Risk Group for the Disease hydrops fetalis due to haemolytic disease - Men and Women aged 0

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In Men diagnosis is most often set at age 0-1
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Less common in men the disease occurs at Age 0-95+Less common in women the disease occurs at Age 0-95+
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In Women diagnosis is most often set at age 0-1

Disease Features hydrops fetalis due to haemolytic disease

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Absence or low individual and public risk
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Hydrops fetalis due to haemolytic disease - what does this mean

Hydrops fetalis due to haemolytic disease occurs when the mother's immune system produces antibodies that attack the red blood cells of the fetus, causing anemia and fluid buildup in the fetus. this can lead to heart failure, organ dysfunction, and even death of the fetus.

What happens during the disease - hydrops fetalis due to haemolytic disease

Hydrops fetalis due to haemolytic disease is a condition in which a fetus accumulates fluid in the body cavities due to an abnormally high number of red blood cells being destroyed. this is usually caused by a rh incompatibility between the mother and the fetus, leading to the mother's immune system producing antibodies which attack the red blood cells of the fetus. this leads to haemolysis (destruction of red blood cells) and the accumulation of fluid in the body cavities, resulting in hydrops fetalis.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC) to measure the number of red blood cells and haemoglobin levels
  • Cordocentesis to measure the bilirubin levels in the fetus
  • Ultrasound to detect fluid accumulation in the fetus
  • Amniocentesis to measure the levels of fetal haemoglobin and to detect any infection
  • Fetal Testing for genetic disorders
  • Maternal Testing for antibodies

Treatment and Medical Assistance

Main Goal: To reduce the severity of the haemolytic disease and reduce the risk of hydrops fetalis.
  • Administering intravenous immunoglobulin (IVIG) to reduce the severity of the haemolytic disease.
  • Administering red blood cell transfusions to increase the haemoglobin levels.
  • Administering corticosteroids to reduce the production of red blood cells.
  • Providing supportive care such as monitoring of vital signs and providing oxygen therapy.
  • Performing regular ultrasounds to monitor the status of the fetus.
  • Monitoring the mother's blood for signs of infection.
  • Administering antibiotics to prevent any infections.
  • Administering anticoagulants to prevent clotting.
  • Performing regular fetal echocardiograms to monitor the heart.
  • Performing amniocentesis to detect any genetic abnormalities.
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21 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Hydrops fetalis due to haemolytic disease - Prevention

Hydrops fetalis due to haemolytic disease can be prevented by antenatal monitoring and treatment with rhig, which is an intravenous immunoglobulin, as well as early diagnosis and treatment of rh incompatibility.

Specified forms of the disease

(P56.0) Hydrops fetalis due to isoimmunization
(P56.9) Hydrops fetalis due to other and unspecified haemolytic disease