(P59.3) Neonatal jaundice from breast milk inhibitor

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5 904 402 in individuals diagnosis neonatal jaundice from breast milk inhibitor confirmed

2 325 deaths with diagnosis neonatal jaundice from breast milk inhibitor

Etiology Pathogenesis Clinical Pattern Diagnostics Treatment Prevention

Diagnosis neonatal jaundice from breast milk inhibitor is diagnosed Men are 11.99% more likely than Women

3 306 204

Men receive the diagnosis neonatal jaundice from breast milk inhibitor

321 (less than 0.1%)

Died from this diagnosis.

100

2 598 198

Women receive the diagnosis neonatal jaundice from breast milk inhibitor

2 004 (less than 0.1%)

Died from this diagnosis.

Risk Group for the Disease neonatal jaundice from breast milk inhibitor - Men and Women aged 0

In Men diagnosis is most often set at age 0-5, 15-34

Less common in men the disease occurs at Age 5-14, 35-95+Less common in women the disease occurs at Age 5-9, 45-95+

In Women diagnosis is most often set at age 0-5, 10-44

Disease Features neonatal jaundice from breast milk inhibitor

Absence or low individual and public risk

Neonatal jaundice from breast milk inhibitor - what does this mean

Neonatal jaundice from breast milk inhibitor occurs when a newborn's liver is unable to effectively process a substance in the mother's breast milk that inhibits the normal breakdown of bilirubin, a yellow pigment found in bile. this results in an accumulation of bilirubin in the newborn's body, leading to the characteristic yellowish discoloration of the skin and eyes known as jaundice.

What happens during the disease - neonatal jaundice from breast milk inhibitor

Neonatal jaundice from breast milk inhibitor is caused by a decrease in the amount of the enzyme glucuronyl transferase in the liver, which is responsible for breaking down bilirubin in the bloodstream. this decrease can be caused by certain drugs in the mother's milk, such as certain antibiotics, that inhibit the action of the enzyme. as a result, the bilirubin is unable to be broken down and is instead reabsorbed into the bloodstream, leading to a buildup of bilirubin in the baby's body and causing jaundice.

Clinical Pattern

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How does a doctor diagnose

Perform a physical exam to assess for signs of jaundice.
Order a complete blood count (CBC) to measure the levels of bilirubin.
Check the baby’s urine for bilirubin.
Order a transcutaneous bilirubin test.
Order a liver function test.
Order a thyroid function test.
Check for any signs of infection.
Check the baby’s feeding habits.
Check the mother’s diet for any possible inhibitors.

Treatment and Medical Assistance

Main goal: To reduce the levels of bilirubin in the infant's blood and improve their health.

Administer phototherapy to reduce the levels of bilirubin in the infant's blood.
Administer intravenous immunoglobulin (IVIG) to reduce the levels of bilirubin.
Administer exchange transfusions to reduce the levels of bilirubin.
Provide supportive care to the infant, including monitoring vital signs.
Provide breastfeeding and/or formula feeding to the infant.
Monitor the infant's bilirubin levels regularly.
Educate the parents on the importance of monitoring the infant's bilirubin levels.

10 Days of Hospitalization Required

Average Time for Outpatient Care Not Established

Neonatal jaundice from breast milk inhibitor - Prevention

The best way to prevent neonatal jaundice from breast milk inhibitor is to ensure that the mother is eating a balanced diet of foods that are low in galactose, such as dairy and legumes, and avoiding foods that are high in galactose, such as honey and certain fruits. additionally, the mother should ensure that she is taking a multivitamin that contains adequate amounts of vitamin e, which can help prevent the inhibition of breast milk.

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