(D57.0) Sickle-cell anaemia with crisis

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65 661 in individuals diagnosis sickle-cell anaemia with crisis confirmed
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2 472 deaths with diagnosis sickle-cell anaemia with crisis
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4% mortality rate associated with the disease sickle-cell anaemia with crisis

Diagnosis sickle-cell anaemia with crisis is diagnosed Men are 15.12% more likely than Women

37 794

Men receive the diagnosis sickle-cell anaemia with crisis

804 (2.1 %)

Died from this diagnosis.

100
95
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75
70
65
60
55
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15
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27 867

Women receive the diagnosis sickle-cell anaemia with crisis

1 668 (6.0 %)

Died from this diagnosis.

Risk Group for the Disease sickle-cell anaemia with crisis - Men and Women aged 10-14

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In Men diagnosis is most often set at age 0-59, 65-89
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Less common in men the disease occurs at Age 60-64, 90-95+Less common in women the disease occurs at Age 50-54, 90-95+
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In Women diagnosis is most often set at age 0-49, 55-89

Disease Features sickle-cell anaemia with crisis

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Absence or low individual and public risk
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Sickle-cell anaemia with crisis - what does this mean

Sickle-cell anaemia with crisis is a condition caused by a genetic mutation in the haemoglobin molecule. this mutation causes red blood cells to take on a sickle shape, leading to a decrease in the cells' ability to carry oxygen. during a crisis, the sickled cells become stuck in small blood vessels, causing blockages and tissue damage, and leading to extreme pain, organ failure, and even death if not treated.

What happens during the disease - sickle-cell anaemia with crisis

Sickle-cell anaemia with crisis is caused by a genetic mutation of the haemoglobin gene that results in the production of abnormal haemoglobin molecules, known as haemoglobin s. these molecules form into long, rigid rods when exposed to low oxygen levels, causing red blood cells to become rigid and assume a sickle shape. this can lead to red cell destruction, occlusion of small blood vessels, and a lack of oxygen delivery to tissues, resulting in pain and organ damage during a crisis.

Clinical Pattern

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How does a doctor diagnose

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Treatment and Medical Assistance

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11 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Sickle-cell anaemia with crisis - Prevention

The best way to prevent sickle-cell anaemia with crisis is to take preventive measures, such as avoiding dehydration, getting enough rest, and avoiding cold temperatures. additionally, taking prescribed medications as directed, and regular check-ups with a doctor can help to reduce the risk of a crisis.