Poisoning: chloramphenicol group - what does this mean
Poisoning from the chloramphenicol group of drugs occurs when an individual is exposed to higher than recommended doses of the drug, either through accidental ingestion, intentional overdose, or through contaminated food or water. symptoms include nausea, vomiting, headache, fever, and yellowing of the skin and eyes. in severe cases, it can lead to aplastic anemia, which can be fatal.
What happens during the disease - poisoning: chloramphenicol group
Poisoning by the chloramphenicol group of drugs occurs when an individual is exposed to a toxic dose of chloramphenicol or its derivatives. this exposure leads to a decrease in the activity of the enzyme acetylcholinesterase, which is responsible for breaking down the neurotransmitter acetylcholine. a decrease in the activity of this enzyme results in an increase in acetylcholine levels, leading to symptoms such as muscle weakness, dizziness, nausea, vomiting, and even death.
Treatment and Medical Assistance
Main Goal: Treat the Poisoning with Chloramphenicol Group
- Administer activated charcoal to reduce absorption of chloramphenicol
- Monitor vital signs and administer supportive care
- Administer intravenous fluids to maintain hydration and electrolyte balance
- Administer anticonvulsants to control seizures
- Administer antibiotics to reduce secondary bacterial infections
- Monitor renal and hepatic function
- Administer vitamin K to counteract hematological toxicity
- Monitor for signs of anemia
5 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Poisoning: chloramphenicol group - Prevention
The best way to prevent poisoning from the chloramphenicol group is to avoid taking any medications that contain this drug, as well as to be aware of any potential interactions with other medications and substances. furthermore, it is important to always read the label of medications and to follow the recommended dosage instructions. lastly, it is important to seek medical attention immediately if any symptoms of poisoning occur.