Clonus is a symptom characterized by rhythmic, involuntary muscle contractions. It usually manifests as a series of jerking movements that occur in response to a stretching of the muscle. It can occur in any muscle group, but is most common in the ankles, wrists, and elbows. Clonus can be caused by a variety of medical conditions, including neurological disorders, muscle diseases, and certain medications. Treatment depends on the underlying cause.