Pupils of the eyes are the black circles in the center of the eyes that enlarge and contract in response to light. Different sizes of pupils can be a symptom of a variety of illnesses and injuries. It can be caused by an eye infection, an injury to the eye, or a neurological disorder. It can also be caused by certain medications or an imbalance of hormones. Symptoms can range from one pupil being larger than the other, to both pupils being larger than normal. It can develop quickly or slowly over time, and can also cause blurred vision, light sensitivity, and headaches.