Группа заболеваний, вызываемых бактериями из рода bartonella, протекающих с преимущественным поражением эндотелиальных клеток и эритроцитов
Men receive the diagnosis bartonellosis
0 (less than 0.1%)Died from this diagnosis.
Women receive the diagnosis bartonellosis
0 (less than 0.1%)Died from this diagnosis.
В месте проникновения возбудителя образуется первичный аффект – папула, везикула или пустула. Далее с током лимфы возбудитель проникает в лимфатические узлы – развивается лимфаденопатия. При преодолении лимфатического барьера патоген поступает в кровь – наступает бактериемия. Наиболее чувствительными к бартонеллам являются эритроциты и эндотелиальные клетки сосудов, костный мозг, клапаны сердца. Активное размножение возбудителя в эритроцитах и их разрушение вызывает развитие гемолитической анемии.
При острых процессах в клетках эндотелия преобладают некротические изменения, стенка сосудов инфильтрируется лейкоцитами и макрофагами с образованием гранулем, явления пролиферации выражены незначительно. В слизистых оболочках, коже появляются мелкие кровоизлияния. Для хронического течения бартонеллеза характерно образование новых мелких сосудов с формированием ангиоэндотелиом. При состоятельности системы иммунитета образуются антитела с последующей элиминацией возбудителя. В случае иммунодефицитных состояний происходит хронизация процесса с длительной персистенцией бартонелл в крови. Отсутствие лечения в такой ситуации может привести к летальному исходу. У выздоровевших пациентов формируется стойкий иммунитет.
(Muscle ache, Muscular soreness, Muscular discomfort, Muscle tenderness, Muscle strain, Muscle spasm, Muscle twinge, Muscle stiffness, Muscle cramp, Muscle fatigue)
Muscle pain is a symptom of an underlying medical condition. It can range from a dull ache to a sharp, burning sensation and can be localized to one area or throughout the body. It often develops gradually, starting with mild discomfort that progresses over time. Muscle pain can be caused by a varie...
(Arthritis, Rheumatism, Aches, Stiffness, Inflammation, Tenderness, Soreness, Swollen joints, Stabbing pain, Throbbing pain, Sharp pain, Dull ache)
Joint pain is a common symptom that can range from mild to severe. It is often caused by inflammation or injury to the joints, muscles, or tendons. It can be localized to one joint or affect multiple joints. It can be acute, lasting only a few days or chronic, lasting weeks or months. It may manifes...
(Pains in the spleen, Spleen pain, Splenic pain, Abdominal pain, Stomach pain, Gut pain, Hepatomegaly pain, Gastrointestinal pain, Visceral pain, Stabbing pain, Sharp pain)
Pain in the spleen is a symptom that can range from mild to severe. It can start as a dull ache and become more intense over time. It may be localized to the spleen area or radiate to the back, shoulder or abdomen. It can also be accompanied by nausea, vomiting, fever, and chills. Pain in the spleen...
(Swollen lymph nodes, Enlarged lymph glands, Inflamed lymph nodes, Bulging lymph nodes, Tender lymph nodes, Enlarged lymph nodes, Swollen lymph glands, Inflamed lymph glands, Bulging lymph glands, Tender lymph glands)
Enlarged lymph nodes are swellings in the lymphatic system that can range in size from pea-sized to the size of a golf ball. They can develop in the neck, armpit, or groin and are usually painless. They can be caused by infection, inflammation, or cancer and may be accompanied by fever, night sweats...
(Stomach pain, Bellyache, Tummy ache, Abdominal ache, Gut pain, Intestinal pain, Stomachache, Abdomen pain, Gastric pain, Abdominal discomfort)
Abdominal pain is a common symptom that can range from mild to severe. It often presents as a dull, aching sensation in the abdomen, but can also manifest as sharp or cramping pain. It can be localized to one area or spread across the abdomen. It can develop suddenly or gradually, and can be accompa...
(Perspiring, Dampness, Moisture, Drenching, Dewy, Sweaty, Damp, Humid, Wetness, Clammy)
Sweating is a common symptom that can manifest itself in different ways. It can range from mild moisture on the skin to heavy perspiration. It can be localized to one area of the body or be generalized over the entire body. It usually develops in response to heat, exercise, anxiety, or emotional str...
(Fever with shivering, Fever with trembling, Fever with shaking, Fever with rigors, Fever with quivering, Fever with shuddering, Fever with quaking, Fever with shudder, Fever with trembling rigors, Fever with shuddering fits)
Fever with chills is a common symptom of infection, and is characterized by a sudden onset of high body temperature and shivering. It may be accompanied by other symptoms such as sweating, headache, fatigue, body aches, and general weakness. As the body temperature rises, the patient may experience ...
Pale skin is a symptom of anemia or other blood-related issues. It is characterized by a lack of color in the skin, appearing wan and ashen. It may also be accompanied by fatigue, dizziness, and shortness of breath. Pale skin develops gradually due to a decrease in red blood cells or hemoglobin, whi...
(Fever, Pyrexia, Hyperthermia, Heatstroke, Hyperpyrexia, Hyperthermy, Hypertherm, High fever, High temperature, Elevated temperature)
High temperature, also known as fever, is a symptom of infection or illness. It is characterized by an elevated body temperature of 38-42°C (100-107°F). It is usually accompanied by other symptoms such as chills, sweating, headache, and malaise. Fever develops when the body's thermoregulatory system...
(Cephalalgia, Hedache, Pounding head, Throbbing head, Ache, Pounding pain, Throbbing pain, Head pain, Migraine, Tension headache)
Headache is a common symptom that can range from mild to severe. It typically develops gradually and can be localized or generalized. Common types of headache include tension-type, migraine, cluster, and sinus headaches, each with their own unique characteristics and manifestations. Tension-type hea...
Hemorrhage under the skin is a symptom characterized by the presence of blood or fluid under the skin. It may appear as a bruise, lump, or discoloration. It usually develops after a trauma or injury to the skin, but can also occur due to a medical condition. The type of hemorrhage can vary, ranging ...
(Bumps, Pimples, Lesions, Nodules, Pustules, Wheals, Blisters, Acne, Cysts)
Papules are small, raised bumps on the skin that can range in size from a few millimeters to a few centimeters. They are usually firm and can be red, pink, or skin-colored. Papules can develop gradually or suddenly and may be itchy or painful. They can be caused by a variety of conditions, such as a...
(Hepatomegaly, Hepatic enlargement, Liver swelling, Hepatitis, Hepatomegalic, Hepatomegalia, Hepatosplenomegaly, Hepatomegalies, Hepatomegaly syndrome, Hepatic enlargement disorder)
Liver enlargement is a symptom of an underlying medical condition. It is characterized by an increase in the size of the liver, which can be felt in the right upper abdomen. It may develop gradually or suddenly, and can be accompanied by pain, nausea, vomiting, and jaundice. It can manifest as an en...
(Tiredness, Exhaustion, Lethargy, Lassitude, Weariness, Burn-out, Weakness, Malaise, Lack of energy, Lack of strength, Listlessness)
Fatigue is a common symptom that can range from mild to severe. It is usually characterized by a feeling of tiredness and exhaustion that can range from mild to severe. It can develop gradually over time or suddenly, and can be caused by a variety of factors, including physical or mental stress, sle...
(Shivering, Goosebumps, Feverish, Chilliness, Shuddering, Freezing, Frosty, Icy, Coldness, Numbness)
Chills are a sudden feeling of coldness accompanied by shivering and a rise in body temperature. They can be caused by exposure to cold temperatures, infections, or emotional stress. Chills typically start with a feeling of coldness and goosebumps, followed by shivering, and then a rise in body temp...