(D64.1) Secondary sideroblastic anaemia due to disease

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4 889 367 in individuals diagnosis secondary sideroblastic anaemia due to disease confirmed
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90 104 deaths with diagnosis secondary sideroblastic anaemia due to disease
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2% mortality rate associated with the disease secondary sideroblastic anaemia due to disease

Diagnosis secondary sideroblastic anaemia due to disease is diagnosed Women are 6.31% more likely than Men

2 290 469

Men receive the diagnosis secondary sideroblastic anaemia due to disease

40 996 (1.8 %)

Died from this diagnosis.

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2 598 898

Women receive the diagnosis secondary sideroblastic anaemia due to disease

49 108 (1.9 %)

Died from this diagnosis.

Risk Group for the Disease secondary sideroblastic anaemia due to disease - Men aged 75-79 and Women aged 80-84

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In Men diagnosis is most often set at age 0-95+
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in in men, the disease manifests at any agein in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features secondary sideroblastic anaemia due to disease

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Absence or low individual and public risk
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Secondary sideroblastic anaemia due to disease - what does this mean

Secondary sideroblastic anaemia due to disease is a condition caused by an underlying medical condition such as chronic kidney disease, cancer, or certain medications. it is characterized by an abnormality in the production of red blood cells, resulting in a decrease in the number of red blood cells and an increase in the number of iron-containing cells called sideroblasts. the decrease in red blood cells leads to anemia, which can cause fatigue, paleness, and shortness of breath. treatment of the underlying condition can help to improve symptoms.

What happens during the disease - secondary sideroblastic anaemia due to disease

Secondary sideroblastic anaemia is a type of anaemia caused by an underlying disease that affects the production of red blood cells. it is caused by a defect in the heme biosynthesis pathway, which results in an accumulation of iron in the mitochondria of the red blood cell precursors. this iron accumulation disrupts the normal maturation of red blood cells and leads to the formation of abnormal red blood cells. these abnormal red blood cells are unable to carry oxygen efficiently, leading to anaemia.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Reticulocyte Count
  • Serum Iron Studies
  • Bone Marrow Biopsy
  • Serum Ferritin Level
  • Serum Transferrin Saturation
  • Serum Vitamin B12 Level
  • Serum Folate Level
  • Serum Copper Level
  • Liver Function Tests
  • Serum Alpha-Fetoprotein Level
  • Genetic Testing

Treatment and Medical Assistance

Main goal of the treatment: To improve the production of healthy red blood cells and reduce the symptoms of anaemia.
  • Administering Vitamin B6
  • Administering Folic Acid
  • Administering Iron Supplements
  • Prescribing Antibiotics to treat any underlying infections
  • Prescribing Corticosteroids to reduce inflammation
  • Prescribing Immunosuppressants to reduce the body's immune response
  • Prescribing Blood Transfusions to increase the number of healthy red blood cells
  • Performing Bone Marrow Transplants to replace unhealthy bone marrow with healthy bone marrow
  • Performing Stem Cell Transplants to replace unhealthy stem cells with healthy stem cells
  • Performing Gene Therapy to correct any genetic abnormalities causing the disease
  • Monitoring the patient's condition and adjusting the treatment plan as necessary
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13 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Secondary sideroblastic anaemia due to disease - Prevention

Secondary sideroblastic anaemia due to disease can be prevented by maintaining a healthy lifestyle, including regular exercise, a balanced diet, avoiding alcohol and smoking, and managing any underlying chronic conditions such as diabetes or hypertension. regular check-ups with a doctor are also recommended to identify any early signs of anaemia.