Acute tubulo-interstitial nephritis - what does this mean
Acute tubulo-interstitial nephritis is an inflammatory disorder of the kidneys caused by an immune reaction to certain drugs or infections. it results in inflammation of the kidney tubules and interstitium, leading to decreased kidney function and increased levels of protein and white blood cells in the urine.
What happens during the disease - acute tubulo-interstitial nephritis
Acute tubulo-interstitial nephritis is an inflammation of the renal tubules and interstitium caused by an immune response to a variety of antigens, including drugs, infections, and autoimmune diseases. it is characterized by an influx of inflammatory cells, such as lymphocytes and macrophages, which cause damage to the renal tubules and interstitium, leading to the release of inflammatory mediators, such as cytokines, chemokines, and reactive oxygen species. these mediators cause further damage to the renal tissue, leading to the development of edema, proteinuria, and ultimately renal failure.
Acute tubulo-interstitial nephritis - Prevention
Acute tubulo-interstitial nephritis can be prevented by avoiding exposure to certain drugs and environmental toxins, maintaining a healthy lifestyle with a balanced diet and regular exercise, and avoiding smoking and excessive alcohol consumption. vaccination against certain infections, such as hepatitis b, may also help to prevent the disease.