DocSym
β
Searchsearch
Search
(D83.0) Common variable immunodeficiency with predominant abnormalities of b-cell numbers and function
More details coming soon
174 785 in individuals diagnosis common variable immunodeficiency with predominant abnormalities of b-cell numbers and function confirmed
3 186 deaths with diagnosis common variable immunodeficiency with predominant abnormalities of b-cell numbers and function
2% mortality rate associated with the disease common variable immunodeficiency with predominant abnormalities of b-cell numbers and function
Diagnosis common variable immunodeficiency with predominant abnormalities of b-cell numbers and function is diagnosed Men are 19.46% more likely than Women
104 402
Men receive the diagnosis common variable immunodeficiency with predominant abnormalities of b-cell numbers and function
1 828 (1.8 %)Died from this diagnosis.
100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
70 383
Women receive the diagnosis common variable immunodeficiency with predominant abnormalities of b-cell numbers and function
1 358 (1.9 %)Died from this diagnosis.
Risk Group for the Disease common variable immunodeficiency with predominant abnormalities of b-cell numbers and function - Men and Women aged 0-5
In Men diagnosis is most often set at age 0-64, 70-89
Less common in men the disease occurs at Age 65-69, 90-95+Less common in women the disease occurs at Age 80-89, 95+
In Women diagnosis is most often set at age 0-79, 90-94
Disease Features common variable immunodeficiency with predominant abnormalities of b-cell numbers and function
Absence or low individual and public risk
Common variable immunodeficiency with predominant abnormalities of b-cell numbers and function - what does this mean
Common variable immunodeficiency with predominant abnormalities of b-cell numbers and function is a rare, inherited disorder caused by genetic mutations that affect the development and function of b-cells. this results in a decrease in the number of b-cells and an impaired ability to produce antibodies, leading to recurrent infections and other immune system malfunctions.
What happens during the disease - common variable immunodeficiency with predominant abnormalities of b-cell numbers and function
Common variable immunodeficiency (cvid) is an immunodeficiency disorder characterized by impaired b-cell numbers and function. it is caused by an impaired ability of b-cells to produce antibodies, leading to an increased susceptibility to infections. this is thought to be due to a combination of genetic, environmental and immunological factors. in some cases, mutations in genes involved in b-cell development and function can lead to an impaired ability to produce antibodies, resulting in cvid. additionally, environmental factors such as exposure to certain viruses or other pathogens can also contribute to a decrease in b-cell numbers and function.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete blood count (CBC)
- Flow cytometry analysis
- Immunoglobulin levels
- T-cell receptor excision circles (TRECs) assay
- Immunophenotyping
- Immunoglobulin gene rearrangement studies
- Functional B-cell assays
- Antibody titers
- Complement levels
Treatment and Medical Assistance
Main Goal: To improve B-cell numbers and function
- Administering immunoglobulin replacement therapy
- Administering corticosteroids
- Administering Rituximab
- Administering intravenous immunoglobulin
- Administering Azathioprine
- Administering Cyclosporine
- Administering Splenectomy
- Administering Antibiotics
- Administering Anti-viral Medications
- Providing Vaccinations
- Providing Allergen Immunotherapy
- Providing Nutritional Support
- Providing Physical Therapy
- Providing Occupational Therapy
- Providing Psychological Support
10 Days of Hospitalization Required
126 Hours Required for Outpatient Treatment
Common variable immunodeficiency with predominant abnormalities of b-cell numbers and function - Prevention
The best way to prevent common variable immunodeficiency with predominant abnormalities of b-cell numbers and function is to maintain a healthy lifestyle, including eating a balanced diet, exercising regularly, and getting adequate sleep. vaccinations also play an important role in prevention, as they can help to strengthen the immune system and reduce the risk of infection. additionally, it is important to avoid contact with people who have contagious illnesses.