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(E24.3) Ectopic acth syndrome
More details coming soon
214 832 in individuals diagnosis ectopic acth syndrome confirmed
3 085 deaths with diagnosis ectopic acth syndrome
1% mortality rate associated with the disease ectopic acth syndrome
Diagnosis ectopic acth syndrome is diagnosed Women are 42.10% more likely than Men
62 196
Men receive the diagnosis ectopic acth syndrome
915 (1.5 %)Died from this diagnosis.
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152 636
Women receive the diagnosis ectopic acth syndrome
2 170 (1.4 %)Died from this diagnosis.
Risk Group for the Disease ectopic acth syndrome - Men aged 20-24 and Women aged 55-59
In Men diagnosis is most often set at age 0-1, 5-84
Less common in men the disease occurs at Age 0-5, 85-95+Less common in women the disease occurs at Age 90-95+
In Women diagnosis is most often set at age 0-89
Disease Features ectopic acth syndrome
Absence or low individual and public risk
Ectopic acth syndrome - what does this mean
Ectopic acth syndrome is a rare disorder caused by the production of excessive amounts of the hormone acth from a non-pituitary source, usually a tumor in the chest or abdomen. this leads to overproduction of cortisol and other hormones, resulting in a variety of symptoms such as weight gain, high blood pressure, diabetes, and cushing's syndrome.
What happens during the disease - ectopic acth syndrome
Ectopic acth syndrome is a rare disorder caused by the production of excess adrenocorticotropic hormone (acth) from a non-pituitary source, such as a tumor. this excess acth causes an overproduction of cortisol, leading to a number of clinical features including obesity, hypertension, glucose intolerance, and hypokalemia. additionally, the presence of a tumor can cause direct compression of the pituitary, resulting in decreased production of other hormones, such as growth hormone, and can lead to further endocrine abnormalities.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Physical exam to determine the size of the tumor
- Blood tests to measure cortisol levels in the blood
- Imaging tests such as CT scan or MRI of the chest and abdomen to look for a tumor
- Urine tests to measure cortisol levels
- Pituitary function tests to measure the levels of other hormones in the blood
- Genetic testing to identify mutations in the genes that are associated with Ectopic ACTH Syndrome
Treatment and Medical Assistance
Main goal of the treatment: To reduce the overproduction of cortisol and restore the body's natural hormone balance.
- Administer a medication to reduce the production of cortisol
- Monitor cortisol levels regularly
- Administer replacement hormones to restore the body's natural hormone balance
- Provide lifestyle advice to reduce stress and manage symptoms
- Refer to a specialist if necessary
- Monitor for any adverse reactions to medications
- Provide regular follow-up care
14 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Ectopic acth syndrome - Prevention
The best way to prevent ectopic acth syndrome is to recognize and address any underlying medical conditions that can cause the syndrome, such as tumors or infections, as soon as possible. additionally, it is important to maintain regular check-ups with your doctor, as early detection and treatment can help prevent the development of the syndrome.