(E84) Cystic fibrosis

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580 693 in individuals diagnosis cystic fibrosis confirmed

10 360 deaths with diagnosis cystic fibrosis

2% mortality rate associated with the disease cystic fibrosis

Etiology Pathogenesis Clinical Pattern Diagnostics Treatment Prevention

Diagnosis cystic fibrosis is diagnosed Women are 3.58% more likely than Men

279 960

Men receive the diagnosis cystic fibrosis

4 512 (1.6 %)

Died from this diagnosis.

100

300 733

Women receive the diagnosis cystic fibrosis

5 848 (1.9 %)

Died from this diagnosis.

Risk Group for the Disease cystic fibrosis - Men aged 15-19 and Women aged 10-14

In Men diagnosis is most often set at age 0-79

Less common in men the disease occurs at Age 80-95+Less common in women the disease occurs at Age 85-95+

In Women diagnosis is most often set at age 0-84

Disease Features cystic fibrosis

Non-contagious

High individual risk, low public risk

Cystic fibrosis - what does this mean

Cystic fibrosis is an inherited disorder caused by a mutation in the cystic fibrosis transmembrane conductance regulator (cftr) gene. this gene produces a protein that helps regulate the movement of salt and water in and out of cells, resulting in the production of thick, sticky mucus that can block the airways, leading to respiratory and digestive problems.

What happens during the disease - cystic fibrosis

Cystic fibrosis is a genetic disorder caused by a mutation in the gene that encodes the cystic fibrosis transmembrane conductance regulator (cftr) protein. this protein is responsible for transporting chloride ions across the cell membrane, which helps to maintain the balance of salt and water in the body. when the cftr protein is mutated, it results in thick, sticky mucus that accumulates in the lungs, pancreas, and other organs, leading to chronic inflammation and infection. over time, this can lead to respiratory and digestive problems, as well as other complications.

Clinical Pattern

More details coming soon

How does a doctor diagnose

Sweat Test
Genetic Testing
Lung Function Tests
Chest X-Ray
CT Scan
Pulmonary Function Test
Sputum Culture
Stool Test

Treatment and Medical Assistance

Main Goal: Treating Cystic Fibrosis

Administering medications to reduce inflammation and thin mucus
Providing nutritional counseling and support
Encouraging physical activity
Providing respiratory therapy to reduce mucus buildup
Administering antibiotics to treat infections
Performing lung transplant surgery, if necessary
Providing emotional support and counseling

21 Days of Hospitalization Required

Average Time for Outpatient Care Not Established

Cystic fibrosis - Prevention

The best way to prevent cystic fibrosis is to ensure that all individuals receive appropriate genetic counseling and testing prior to conception. additionally, it is important to avoid smoking and to maintain a healthy lifestyle with a balanced diet and regular exercise.

Main symptoms of the disease cystic fibrosis

Intussusception

(Intestinal invagination, Bowel telescoping, Intestinal infolding, Bowel intussusception, Enteric reduplication, Enteric invagination)

Intussusception is a condition where part of the intestine slides into an adjacent part of the intestine. It is usually seen in children under the age of 5, and is characterized by abdominal pain, vomiting, and bloody stool. As the condition progresses, the abdominal pain may become severe and the p...

Age: 1 to 100Accociated with 8 diseases

Vomit

Vomiting is the forceful expulsion of stomach contents through the mouth. It can be accompanied by nausea, abdominal pain, and sweating. Vomiting can be caused by a variety of conditions, such as food poisoning, motion sickness, viral infections, and migraine headaches. Symptoms can range from mild ...

Age: any ageAccociated with 149 diseases

Abnormal weight loss

(Unintended weight loss, Unexplained weight loss, Rapid weight loss, Excessive weight loss, Drastic weight loss, Sudden weight loss, Substantial weight loss, Significant weight loss, Unwanted weight loss, Unexpected weight loss)

Abnormal weight loss is a symptom of an underlying medical condition. It is characterized by a significant decrease in body weight that is not related to changes in diet or exercise habits. It may be accompanied by fatigue, decreased appetite, nausea, and other symptoms. It can develop gradually or ...

Age: any ageAccociated with 97 diseases

Insomnia

(Sleeplessness, Sleep deprivation, Awakeness, Restlessness, Insomnolence, Nocturnal wakefulness, Sleepless nights, Sleeplessness disorder, Sleep disorder, Sleep difficulty, Sleep problem, Sleep deprivation disorder, Sleep disturbance)

Insomnia is a sleep disorder characterized by difficulty falling asleep and/or staying asleep. It can manifest in different ways, including difficulty initiating sleep, waking up multiple times throughout the night, waking up too early, and feeling unrefreshed after sleep. It can be caused by variou...

Age: 1 to 100Accociated with 75 diseases

Cough

(Hack, Wheeze, Hacking, Coughing, Rales, Choking, Gasping, Barking, Hemoptysis, Whooping, Pertussis)

Coughing is a reflex action that helps clear airways of irritants and mucus. It usually begins as a dry, tickling sensation in the back of the throat that causes an uncontrollable urge to cough. It can range from a mild, intermittent annoyance to a severe, hacking cough that produces thick mucus. It...

Age: 1 to 100Accociated with 116 diseases

Specified forms of the disease

(E84.0) Cystic fibrosis with pulmonary manifestations
(E84.1) Cystic fibrosis with intestinal manifestations
(E84.8) Cystic fibrosis with other manifestations
(E84.9) Cystic fibrosis, unspecified

Diseases with similar symptoms