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(L10.0) Pemphigus vulgaris
More details coming soon
190 040 in individuals diagnosis pemphigus vulgaris confirmed
3 763 deaths with diagnosis pemphigus vulgaris
2% mortality rate associated with the disease pemphigus vulgaris
Diagnosis pemphigus vulgaris is diagnosed Women are 15.67% more likely than Men
80 132
Men receive the diagnosis pemphigus vulgaris
1 911 (2.4 %)Died from this diagnosis.
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109 908
Women receive the diagnosis pemphigus vulgaris
1 852 (1.7 %)Died from this diagnosis.
Risk Group for the Disease pemphigus vulgaris - Men aged 55-59 and Women aged 60-64
In Men diagnosis is most often set at age 0-1, 5-89
Less common in men the disease occurs at Age 0-5, 90-95+in in women, the disease manifests at any age
In Women diagnosis is most often set at age 0-95+
Disease Features pemphigus vulgaris
Absence or low individual and public risk
Pemphigus vulgaris - what does this mean
Pemphigus vulgaris is an autoimmune disorder in which the body's immune system mistakenly attacks the skin and mucous membranes, causing painful blisters and sores. it is caused by an abnormal production of antibodies, which attack the proteins that hold the top layer of skin cells together. this results in the formation of blisters and sores that can be painful and itchy.
What happens during the disease - pemphigus vulgaris
Pemphigus vulgaris is an autoimmune condition in which the body's own immune system attacks the skin and mucous membranes, resulting in the formation of blisters and erosions. this is caused by antibodies that are produced by the body, which attack the proteins that hold the cells of the epidermis together. this leads to a breakdown of the skin barrier, resulting in the formation of painful blisters and erosions.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Physical examination
- Biopsy of affected skin
- Immunofluorescence testing of skin biopsy specimens
- Blood tests to check for antibodies to desmoglein
- CT scans
- X-rays
- MRI scans
- Electron microscopy
Treatment and Medical Assistance
Main goal of the treatment: To reduce the severity of the symptoms and prevent the progression of the disease.
- Administering corticosteroids, such as prednisone, to reduce inflammation and suppress the immune system.
- Prescribing immunosuppressants, such as methotrexate, to suppress the immune system.
- Prescribing antibiotics, such as tetracycline, to reduce inflammation.
- Prescribing topical medications, such as corticosteroids, to reduce inflammation.
- Prescribing anti-inflammatory medications, such as ibuprofen, to reduce inflammation.
- Prescribing topical retinoids, such as tazarotene, to reduce inflammation.
- Prescribing phototherapy, such as ultraviolet light therapy, to reduce inflammation.
- Prescribing oral medications, such as dapsone, to reduce inflammation.
- Prescribing biologic therapies, such as rituximab, to reduce inflammation.
- Encouraging a healthy lifestyle, including a balanced diet and regular exercise.
- Managing stress levels to reduce the severity of symptoms.
15 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Pemphigus vulgaris - Prevention
The best way to prevent pemphigus vulgaris is to avoid exposure to environmental triggers such as sunlight, extreme temperatures, stress, and certain medications. it is also important to practice good skin hygiene and use gentle cleansers and moisturizers to keep the skin healthy and reduce the risk of infection.