(E52) Niacin deficiency [pellagra]

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1 296 in individuals diagnosis niacin deficiency [pellagra] confirmed
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1 476 deaths with diagnosis niacin deficiency [pellagra]
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114% mortality rate associated with the disease niacin deficiency [pellagra]

Diagnosis niacin deficiency [pellagra] is diagnosed Men are 3.09% more likely than Women

668

Men receive the diagnosis niacin deficiency [pellagra]

1 476 (221.0 %)

Died from this diagnosis.

100
95
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85
80
75
70
65
60
55
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45
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5
0
628

Women receive the diagnosis niacin deficiency [pellagra]

0 (less than 0.1%)

Died from this diagnosis.

Risk Group for the Disease niacin deficiency [pellagra] - Men aged 70-74 and Women aged 40-44

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In Men diagnosis is most often set at age 70-74
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Less common in men the disease occurs at Age 0-69, 75-95+Less common in women the disease occurs at Age 0-39, 45-69, 75-95+
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In Women diagnosis is most often set at age 40-44, 70-74

Disease Features niacin deficiency [pellagra]

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Absence or low individual and public risk
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Niacin deficiency [pellagra] - what does this mean

Niacin deficiency, or pellagra, is caused by a lack of dietary niacin, which is an essential vitamin. it is most commonly seen in developing countries with poor diets, where people rely heavily on maize as a staple food. symptoms include skin lesions, digestive problems, and mental confusion. in severe cases, it can lead to death.

What happens during the disease - niacin deficiency [pellagra]

Niacin deficiency, or pellagra, is caused by an inadequate intake of dietary niacin or its precursor tryptophan. this deficiency leads to a decrease in the activity of the enzyme nicotinamide adenine dinucleotide (nad), which is involved in many metabolic pathways including the breakdown of carbohydrates, proteins, and fats. as a result, the body is unable to properly utilize these nutrients, leading to a wide range of symptoms including dermatitis, diarrhea, dementia, and eventually death.

Clinical Pattern

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How does a doctor diagnose

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Treatment and Medical Assistance

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6 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Niacin deficiency [pellagra] - Prevention

The best way to prevent niacin deficiency (pellagra) is to ensure a balanced and varied diet that includes foods rich in niacin, such as fish, poultry, lean meats, nuts, legumes, and whole grains. additionally, niacin supplements can be taken as a preventative measure.

Main symptoms of the disease niacin deficiency [pellagra]

Prostration

(Collapse, Fatigue, Lassitude, Exhaustion, Debility, Weakness, Languor, Listlessness, Lethargy, Debilitation, Enervation, Burnout)

Prostration is a symptom of severe physical and mental exhaustion, characterized by a feeling of extreme weakness and a strong desire to lie down. It is usually accompanied by a feeling of heaviness in the limbs and a lack of energy, which can be accompanied by a feeling of nausea or dizziness. Pros...

Age: any ageAccociated with 58 diseases

Decreased appetite

(Diminished hunger, Loss of appetite, Lack of appetite, Decreased hunger, Reduced appetite, Anorexia, Poor appetite, Decreased intake, Lack of interest in food)

Decreased appetite is a symptom that can manifest in a variety of ways. It can manifest as a lack of interest in food, difficulty eating, or a lack of hunger. This symptom can develop gradually over time or suddenly. It can be caused by a variety of medical conditions, medications, or psychological ...

Age: any ageAccociated with 119 diseases
Rash

Rash

(Eruption, Dermatitis, Skin irritation, Hives, Itching, Inflammation, Redness, Bumps, Blotches, Scaly patch)

A rash is an area of irritated or swollen skin. It may appear as red bumps, patches, or blisters and can be itchy, dry, or painful. It can develop suddenly or over time and can be caused by a variety of factors, including allergies, infections, and irritants. Common rashes include eczema, hives, and...

Age: any ageAccociated with 103 diseases

Nausea

(Upset stomach, Queasiness, Queasy feeling, Stomach discomfort, Gastric unease, Stomach churning, Stomach upset, Stomachache, Feeling sick, Feeling queasy, Stomach queasiness, Feeling nauseous, Feeling nauseated, Nauseousness)

Nausea is an unpleasant feeling in the upper abdomen that may be accompanied by an urge to vomit. It can range from mild to severe and can be accompanied by symptoms such as sweating, dizziness, and increased salivation. Nausea can be caused by a variety of stimuli, including motion sickness, certai...

Age: 1 to 100Accociated with 217 diseases

Vomit

Vomiting is the forceful expulsion of stomach contents through the mouth. It can be accompanied by nausea, abdominal pain, and sweating. Vomiting can be caused by a variety of conditions, such as food poisoning, motion sickness, viral infections, and migraine headaches. Symptoms can range from mild ...

Age: any ageAccociated with 149 diseases

Diarrhea

(Loose stools, Runny stool, Frequent bowel movements, Watery stool, Bowel incontinence, Unformed stool, Intestinal distress, Stomach upset, Intestinal disorder, Bowel irregularity)

Diarrhea is an increase in the frequency, volume and fluid content of bowel movements. It can range from loose, watery stools to frequent, watery bowel movements. It is often accompanied by abdominal pain, cramping, bloating, gas and an urgent need to use the bathroom. Diarrhea can be acute, lasting...

Age: any ageAccociated with 103 diseases

Irritability and anger

(Agitation, Annoyance, Frustration, Hostility, Impatience, Impetuosity, Indignation, Irascibility, Irritation, Resentment, Testiness, Upset)

Irritability and anger are common symptoms of many psychological and physical health issues. It is characterized by frequent outbursts of anger and frustration, often in response to minor issues. It can be accompanied by feelings of restlessness, agitation, and difficulty controlling emotions. It of...

Age: 5 to 100Accociated with 53 diseases

Dementia

Dementia is a symptom of a wide range of conditions that affect the brain. It is characterised by a decline in cognitive function, including memory, language, problem-solving, and judgement. It can also affect behaviour, emotions, and the ability to perform everyday activities. Symptoms typically de...

Age: 1 to 100Accociated with 19 diseases

Skin redness

(Rash, Erythema, Flushing, Inflammation, Blotchiness, Itching, Burning, Irritation, Discoloration, Tenderness)

Skin redness is a common symptom of many medical conditions. It can range from a mild pink flush on the cheeks to a deep red rash across the body. It is often accompanied by itching, burning, and swelling. It can develop quickly or over time, and can be triggered by a variety of factors such as alle...

Age: 1 to 100Accociated with 64 diseases

Specified forms of the disease

(L94.0) Localized scleroderma [morphea]
(L94.1) Linear scleroderma
(L94.2) Calcinosis cutis
(L94.3) Sclerodactyly
(L94.4) Gottron papules
(L94.5) Poikiloderma vasculare atrophicans
(L94.6) Ainhum
(L94.8) Other specified localized connective tissue disorders
(L94.9) Localized connective tissue disorder, unspecified