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Men receive the diagnosis unspecified nephritic syndrome
5 145 (4.6 %)Died from this diagnosis.
Women receive the diagnosis unspecified nephritic syndrome
4 105 (4.3 %)Died from this diagnosis.
Ключевым звеном развития нефритического синдрома считается отложение иммунных комплексов в почечных клубочках в промежутке между базальными мембранами и отростками подоцитов. Возникает выраженная воспалительная реакция, снижается скорость клубочковой фильтрации, в организме задерживаются вода и соли. Повышенный уровень натрия и активация РААС провоцируют увеличение объема внеклеточной жидкости.
В условиях гипергидратации усиливается сердечный выброс, происходит отек сосудистых стенок и увеличивается их чувствительность к катехоламинам, уменьшается выработка простагландинов и кининов. Такие механизмы вызывают стойкую артериальную гипертензию. Перераспределение жидкости с преимущественным депонированием в рыхлой клетчатке становится причиной отеков.
Воспалительный процесс повреждает капилляры клубочков и нарушает процессы фильтрации, в результате чего эритроциты и крупномолекулярные белки плазмы попадают в первичную мочу. В мочевом осадке появляются цилиндры, возникает микро- или макрогематурия.
(Fluid retention, Swelling, Puffiness, Fluid accumulation, Bloating, Hydrops, Dropsy, Congestion, Inflammation)
Tissue edema is an accumulation of fluid in the interstitial space of the body. It can occur in any part of the body, but is most commonly seen in the extremities, face, and abdomen. It is characterized by swelling, tenderness, and a feeling of tightness in the affected area. It may develop graduall...
(Stomach pain, Bellyache, Tummy ache, Abdominal ache, Gut pain, Intestinal pain, Stomachache, Abdomen pain, Gastric pain, Abdominal discomfort)
Abdominal pain is a common symptom that can range from mild to severe. It often presents as a dull, aching sensation in the abdomen, but can also manifest as sharp or cramping pain. It can be localized to one area or spread across the abdomen. It can develop suddenly or gradually, and can be accompa...
(Hypertension, Hypertensive, High blood pressure, Bp, Elevated pressure, Raised pressure, Cardiac stress, Tension, Strain)
High pressure headache is a type of headache that is characterized by a feeling of pressure or tightness around the head. It usually develops slowly, beginning as a dull ache and gradually intensifying to a throbbing or pounding sensation. It can be accompanied by other symptoms such as sensitivity ...
(Swelling, Water retention, Bloating, Puffiness, Inflammation, Fluid retention, Hydrops, Dropsy, Oedema, Hydrothorax)
General edema is swelling caused by excess fluid trapped in the body's tissues. It can affect any part of the body, but is most noticeable in the feet, ankles, legs, hands, and face. It can develop suddenly or gradually. Symptoms range from mild to severe, and may include pain, itching, or a feeling...
(Hematuria, Urine with blood, Blood in urine, Discolored urine, Pink urine, Red urine, Maroon urine, Brown urine)
Blood in the urine, also known as hematuria, is a symptom that occurs when red blood cells are present in the urine. It can range from a few drops to a large amount of blood and may be accompanied by pain, a burning sensation, or difficulty urinating. The color of the urine may be pink, red, or brow...
(Overweight, Corpulence, Corpulency, Heaviness, Plumpness, Ponderosity, Portliness, Avoirdupois, Fleshy, Gain, Rotundity)
Obesity is a condition in which excess body fat accumulates to the point of negative health effects. It is usually defined as having a body mass index (BMI) of 30 or higher. It can develop gradually over time, due to an imbalance between energy intake (eating too much) and energy expenditure (not be...
Weakness is a lack of strength and energy that can range from mild to severe. It can be a symptom of a wide range of conditions, including physical and mental exhaustion, chronic illnesses, and certain medications. It can also be caused by a lack of nutrients, dehydration, or an underlying medical c...
(Absence of urine, Decreased urine output, Low urine output, Reduced urine production, Suppressed urine production)
Anuria and oliguria are medical terms used to describe a decreased output of urine. Anuria is a complete absence of urine and oliguria is a decreased output of urine. These symptoms can be caused by a number of conditions, such as kidney failure, dehydration, or blockage in the urinary tract. Sympto...
(Black urine, Deep colored urine, Cola colored urine, Tea-colored urine, Brown urine, Amber urine, Rusty urine, Soda-colored urine, Coffee-colored urine)
Dark urine is a symptom of a medical condition where the urine takes on a darker hue, typically yellow or brown. It can be caused by dehydration, liver disease, certain medications, or blood in the urine. It can also be caused by eating certain foods or drinks. Dark urine can develop over time or be...
(Upset stomach, Queasiness, Queasy feeling, Stomach discomfort, Gastric unease, Stomach churning, Stomach upset, Stomachache, Feeling sick, Feeling queasy, Stomach queasiness, Feeling nauseous, Feeling nauseated, Nauseousness)
Nausea is an unpleasant feeling in the upper abdomen that may be accompanied by an urge to vomit. It can range from mild to severe and can be accompanied by symptoms such as sweating, dizziness, and increased salivation. Nausea can be caused by a variety of stimuli, including motion sickness, certai...
(Cephalalgia, Hedache, Pounding head, Throbbing head, Ache, Pounding pain, Throbbing pain, Head pain, Migraine, Tension headache)
Headache is a common symptom that can range from mild to severe. It typically develops gradually and can be localized or generalized. Common types of headache include tension-type, migraine, cluster, and sinus headaches, each with their own unique characteristics and manifestations. Tension-type hea...
(Dry mouth, Dehydration, Parched, Desiccated, Cotton-mouth, Ravenous, Unquenchable, Excessive drinking, Unsatisfied thirst, Parching)
Thirst is an intense desire to drink liquids. It can be caused by dehydration, illness, or certain medications. It can also be a sign of an underlying medical condition. Symptoms of thirst include feeling dry in the mouth, feeling weak, and having a headache. It can also lead to dizziness, fatigue, ...
(High temperature, Fever, Feverishness, Pyrexia, Hyperthermia, Heat, Warmth, Hyperpyrexia, Hyperthermy, Thermalgia)
Elevated temperature is a symptom of illness where the body temperature is higher than normal. It typically appears as a fever, with the temperature ranging from 37-38°C. It is often accompanied by other symptoms such as chills, body aches, and fatigue. Elevated temperature can develop over a few da...
(Lumbar pain, Backache, Lumbago, Lumbar ache, Back discomfort, Lower backache, Lower back discomfort, Lumbar discomfort, Lower back pain, Lumbar agony)
Lower back pain is characterized by aching or stiffness in the lower back, often radiating down the legs. It can develop suddenly or gradually, and can range in intensity from mild to severe. It can be caused by a number of factors, including injury, overuse, poor posture, obesity, or disease. Its m...