Changes in the structure of the skin

Changes in the structure of the skin can manifest as discoloration, lesions, bumps, blisters, or other abnormalities. These changes can be caused by a variety of factors, including environmental irritants, allergies, infection, and autoimmune diseases. The changes may start as small, localized patches, but can spread and worsen over time. Common symptoms include itching, burning, stinging, and pain. In some cases, the skin may become dry and scaly, or develop a rash. In more severe cases, the skin may become thickened and leathery.