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(N25.1) Nephrogenic diabetes insipidus
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400 174 in individuals diagnosis nephrogenic diabetes insipidus confirmed
2 710 deaths with diagnosis nephrogenic diabetes insipidus
1% mortality rate associated with the disease nephrogenic diabetes insipidus
Diagnosis nephrogenic diabetes insipidus is diagnosed Men are 4.58% more likely than Women
209 247
Men receive the diagnosis nephrogenic diabetes insipidus
1 207 (0.6 %)Died from this diagnosis.
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190 927
Women receive the diagnosis nephrogenic diabetes insipidus
1 503 (0.8 %)Died from this diagnosis.
Risk Group for the Disease nephrogenic diabetes insipidus - Men aged 55-59 and Women aged 60-64
In Men diagnosis is most often set at age 0-94
Less common in men the disease occurs at Age 95+Less common in women the disease occurs at Age 95+
In Women diagnosis is most often set at age 0-94
Disease Features nephrogenic diabetes insipidus
Absence or low individual and public risk
Nephrogenic diabetes insipidus - what does this mean
Nephrogenic diabetes insipidus is a rare disorder where the kidneys are unable to concentrate urine due to a defect in the action of the antidiuretic hormone (adh) on the renal tubules. this results in increased urine production and excessive thirst.
What happens during the disease - nephrogenic diabetes insipidus
Nephrogenic diabetes insipidus is caused by a defect in the renal tubules’ ability to respond to the antidiuretic hormone (adh). this defect can be caused by genetic mutations, endocrine disorders, medications, or toxins, which all prevent the kidney from responding to adh and therefore cause it to excrete large amounts of dilute urine. this leads to excessive thirst and urination, as well as dehydration.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete physical examination
- Urine tests to measure urine concentration and volume
- Blood tests to measure sodium and potassium levels
- Imaging tests such as ultrasound or MRI to evaluate the kidneys
- Genetic testing to identify mutations in the genes responsible for the disease
- CT scan to assess the size and shape of the kidneys
- Kidney biopsy to obtain a sample of kidney tissue for analysis
Treatment and Medical Assistance
Main goal: Treating Nephrogenic diabetes insipidus
- Administering desmopressin
- Monitoring and controlling fluid intake
- Taking diuretics
- Replacing electrolytes
- Taking nonsteroidal anti-inflammatory drugs
- Treating underlying conditions
- Monitoring kidney function
- Maintaining a healthy diet
7 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Nephrogenic diabetes insipidus - Prevention
Nephrogenic diabetes insipidus can be prevented by avoiding certain medications, such as lithium, demeclocycline, and amphotericin b, that can cause the condition. additionally, maintaining proper hydration and proper electrolyte balance can help prevent the condition.