(D46.0) Refractory anaemia without ring sideroblasts, so stated

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2 030 090 in individuals diagnosis refractory anaemia without ring sideroblasts, so stated confirmed
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215 512 deaths with diagnosis refractory anaemia without ring sideroblasts, so stated
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11% mortality rate associated with the disease refractory anaemia without ring sideroblasts, so stated

Diagnosis refractory anaemia without ring sideroblasts, so stated is diagnosed Men are 4.72% more likely than Women

1 062 928

Men receive the diagnosis refractory anaemia without ring sideroblasts, so stated

122 283 (11.5 %)

Died from this diagnosis.

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967 162

Women receive the diagnosis refractory anaemia without ring sideroblasts, so stated

93 229 (9.6 %)

Died from this diagnosis.

Risk Group for the Disease refractory anaemia without ring sideroblasts, so stated - Men and Women aged 75-79

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In Men diagnosis is most often set at age 0-95+
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in in men, the disease manifests at any agein in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features refractory anaemia without ring sideroblasts, so stated

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Absence or low individual and public risk
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Refractory anaemia without ring sideroblasts, so stated - what does this mean

Refractory anaemia without ring sideroblasts is a type of anemia caused by a genetic mutation that affects the production of red blood cells. this mutation results in the body's inability to produce enough healthy red blood cells and can lead to anemia, fatigue, and other symptoms. it is diagnosed through a combination of blood tests and bone marrow biopsy.

What happens during the disease - refractory anaemia without ring sideroblasts, so stated

Refractory anaemia without ring sideroblasts is a type of myelodysplastic syndrome characterized by ineffective red blood cell production in the bone marrow, resulting in anemia. the underlying cause is a defect in the genetic material of the bone marrow cells, which leads to an inability to produce the necessary proteins for red blood cell production. this defect impairs the ability of the bone marrow to produce enough healthy red blood cells, resulting in anemia.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC) with differential
  • Peripheral Smear
  • Bone Marrow Aspiration and Biopsy
  • Cytogenetic Analysis
  • Flow Cytometry
  • Immunophenotyping
  • Fluorescence In Situ Hybridization (FISH)
  • Molecular Testing

Treatment and Medical Assistance

Main goal of the treatment: To reduce symptoms and treat the underlying cause of refractory anaemia without ring sideroblasts.
  • Blood transfusions
  • Iron chelation therapy
  • Immunosuppressive drugs
  • Growth factors
  • Stem cell transplantation
  • Gene therapy
  • Dietary changes
  • Exercise
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12 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Refractory anaemia without ring sideroblasts, so stated - Prevention

The best way to prevent refractory anaemia without ring sideroblasts is to maintain a healthy lifestyle, including eating a balanced diet, exercising regularly, and avoiding smoking, alcohol, and drugs. additionally, regular check-ups with a doctor can help to identify any early signs of the disease and allow for prompt treatment.