Рефрактерная анемия с избытком бластов с трансформацией - what does this mean
Refractory anemia with excess blasts with transformation is a myelodysplastic syndrome characterized by anemia, excess blasts in the bone marrow, and transformation to acute myeloid leukemia. it is caused by a combination of genetic and environmental factors, resulting in the production of abnormal blood cells.
What happens during the disease - рефрактерная анемия с избытком бластов с трансформацией
Refractory anemia with excess blasts with transformation is a form of myelodysplastic syndrome (mds) characterized by a decrease in red blood cells and an increase in blasts, which are immature white blood cells. the underlying cause of this condition is a genetic mutation in the bone marrow, which leads to an inability to produce healthy blood cells. this mutation disrupts the process of hematopoiesis, resulting in an accumulation of blasts in the bone marrow and a decreased production of mature red blood cells.