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(D52.1) Drug-induced folate deficiency anaemia
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88 431 in individuals diagnosis drug-induced folate deficiency anaemia confirmed
7 252 deaths with diagnosis drug-induced folate deficiency anaemia
8% mortality rate associated with the disease drug-induced folate deficiency anaemia
Diagnosis drug-induced folate deficiency anaemia is diagnosed Women are 12.73% more likely than Men
38 589
Men receive the diagnosis drug-induced folate deficiency anaemia
3 483 (9.0 %)Died from this diagnosis.
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49 842
Women receive the diagnosis drug-induced folate deficiency anaemia
3 769 (7.6 %)Died from this diagnosis.
Risk Group for the Disease drug-induced folate deficiency anaemia - Men aged 75-79 and Women aged 80-84
In Men diagnosis is most often set at age 0-1, 10-39, 45-94
Less common in men the disease occurs at Age 0-9, 40-44, 95+Less common in women the disease occurs at Age 0-5, 10-14, 25-29
In Women diagnosis is most often set at age 0-1, 5-9, 15-24, 30-95+
Disease Features drug-induced folate deficiency anaemia
Absence or low individual and public risk
Drug-induced folate deficiency anaemia - what does this mean
Drug-induced folate deficiency anaemia occurs when medications interfere with the body's ability to absorb or metabolize folate, a b-vitamin needed for red blood cell production. this can lead to a decrease in red blood cells, resulting in anaemia.
What happens during the disease - drug-induced folate deficiency anaemia
Drug-induced folate deficiency anaemia is a type of anaemia caused by the reduced absorption of folate due to certain medications. this can be caused by certain medications that interfere with the absorption of folate in the gut, such as anticonvulsants, methotrexate, sulfasalazine, and antibiotics. these medications can reduce the amount of folate available to the body, leading to a deficiency in folate. the lack of folate results in decreased production of red blood cells, leading to anaemia.
Clinical Pattern
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How does a doctor diagnose
- Complete Blood Count (CBC)
- Peripheral Blood Smear
- Serum Folate Level
- Serum Vitamin B12 Level
- Serum Vitamin B6 Level
- Serum Iron Level
- Serum Ferritin Level
- Serum Transferrin Level
- Serum Total Protein Level
- Urine Analysis
- Bone Marrow Biopsy
Treatment and Medical Assistance
Main Goal: To treat Drug-induced folate deficiency anaemia
- Discontinue the use of drugs that interfere with folate metabolism.
- Administer folate supplements.
- Increase dietary intake of folate-rich foods.
- Administer vitamin B12 supplements.
- Increase dietary intake of vitamin B12-rich foods.
- Provide supportive care to improve the patient's quality of life.
- Monitor patients for signs of folate deficiency anaemia.
- Administer iron supplements.
- Increase dietary intake of iron-rich foods.
14 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Drug-induced folate deficiency anaemia - Prevention
Drug-induced folate deficiency anaemia can be prevented by avoiding medications that interfere with folate metabolism, such as methotrexate, sulfasalazine, and trimethoprim-sulfamethoxazole, as well as alcohol consumption. additionally, it is important to ensure that folate levels are regularly monitored in individuals who are taking medications that can interfere with folate metabolism.