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(D57.1) Sickle-cell anaemia without crisis
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65 661 in individuals diagnosis sickle-cell anaemia without crisis confirmed
2 472 deaths with diagnosis sickle-cell anaemia without crisis
4% mortality rate associated with the disease sickle-cell anaemia without crisis
Diagnosis sickle-cell anaemia without crisis is diagnosed Men are 15.12% more likely than Women
37 794
Men receive the diagnosis sickle-cell anaemia without crisis
804 (2.1 %)Died from this diagnosis.
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27 867
Women receive the diagnosis sickle-cell anaemia without crisis
1 668 (6.0 %)Died from this diagnosis.
Risk Group for the Disease sickle-cell anaemia without crisis - Men and Women aged 10-14
In Men diagnosis is most often set at age 0-59, 65-89
Less common in men the disease occurs at Age 60-64, 90-95+Less common in women the disease occurs at Age 50-54, 90-95+
In Women diagnosis is most often set at age 0-49, 55-89
Disease Features sickle-cell anaemia without crisis
Absence or low individual and public risk
Sickle-cell anaemia without crisis - what does this mean
Sickle-cell anaemia without crisis is caused by a genetic mutation in the haemoglobin gene, which results in red blood cells becoming rigid, sticky and crescent-shaped. this causes them to block small blood vessels, leading to a decrease in oxygen delivery to the body's tissues and organs, resulting in anaemia.
What happens during the disease - sickle-cell anaemia without crisis
Sickle-cell anaemia is a genetic disorder caused by a mutation in the gene that codes for the haemoglobin protein. this mutation results in abnormal haemoglobin molecules that become rigid and sticky when oxygen levels are low, leading to the formation of sickle-shaped red blood cells. these cells are unable to move easily through small blood vessels, resulting in blockage and decreased oxygen delivery to tissues. over time, this can lead to chronic anaemia, organ damage, and other symptoms. without a crisis, the symptoms of sickle-cell anaemia can be managed with medication, regular blood transfusions, and other treatments.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete Blood Count (CBC)
- Hemoglobin Electrophoresis
- Sickle Cell Solubility Test
- High Performance Liquid Chromatography (HPLC)
- Molecular Testing
- Genetic Testing
- Bone Marrow Biopsy
Treatment and Medical Assistance
Main goal of the Treatment: To reduce complications of Sickle-Cell Anaemia and maintain the patient's quality of life.
- Regular monitoring of haemoglobin levels and other blood tests
- Prescription of antibiotics to prevent infections
- Folic acid supplements to boost red blood cell production
- Pain management with medications
- Hydration therapy to help reduce the risk of crises
- Oxygen therapy to help reduce the risk of crises
- Blood transfusions to increase haemoglobin levels
- Regular exercise and a healthy diet
- Avoidance of triggers such as dehydration and extreme temperatures
- Regular check-ups with a haematologist
11 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Sickle-cell anaemia without crisis - Prevention
The best way to prevent sickle-cell anaemia without crisis is to get regular check-ups and take preventive measures such as avoiding dehydration, getting vaccinated, and avoiding smoking. additionally, it is important to maintain a healthy lifestyle, including eating a balanced diet, exercising regularly, and managing stress. taking folic acid supplements may also help to prevent the disease.