(D57.3) Sickle-cell trait

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65 661 in individuals diagnosis sickle-cell trait confirmed
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2 472 deaths with diagnosis sickle-cell trait
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4% mortality rate associated with the disease sickle-cell trait

Diagnosis sickle-cell trait is diagnosed Men are 15.12% more likely than Women

37 794

Men receive the diagnosis sickle-cell trait

804 (2.1 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
27 867

Women receive the diagnosis sickle-cell trait

1 668 (6.0 %)

Died from this diagnosis.

Risk Group for the Disease sickle-cell trait - Men and Women aged 10-14

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In Men diagnosis is most often set at age 0-59, 65-89
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Less common in men the disease occurs at Age 60-64, 90-95+Less common in women the disease occurs at Age 50-54, 90-95+
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In Women diagnosis is most often set at age 0-49, 55-89

Disease Features sickle-cell trait

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Absence or low individual and public risk
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Sickle-cell trait - what does this mean

Sickle-cell trait is an inherited condition in which a person carries one abnormal gene for hemoglobin, the protein in red blood cells responsible for carrying oxygen. this abnormal gene causes the red blood cells to become crescent-shaped instead of round, leading to anemia, pain, and other complications.

What happens during the disease - sickle-cell trait

Sickle-cell trait is caused by a genetic mutation in the hemoglobin molecule, which causes it to take on a sickle shape when exposed to low oxygen levels. this sickle shape causes red blood cells to become rigid and sticky, leading to blockage of small blood vessels and decreased oxygen delivery to the tissues, resulting in anemia, pain, and other symptoms.

Clinical Pattern

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How does a doctor diagnose

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Treatment and Medical Assistance

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11 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Sickle-cell trait - Prevention

The prevention of sickle-cell trait involves a variety of measures, including genetic counseling, pre-pregnancy testing of both partners to determine if they are carriers of the sickle-cell gene, and prenatal screening to identify fetuses at risk for the trait. additionally, individuals of african descent should receive regular screenings to detect the trait or anemia early, and those with the trait should receive preventive care such as vaccinations and regular blood transfusions.