(D59.0) Drug-induced autoimmune haemolytic anaemia

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334 581 in individuals diagnosis drug-induced autoimmune haemolytic anaemia confirmed
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11 068 deaths with diagnosis drug-induced autoimmune haemolytic anaemia
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3% mortality rate associated with the disease drug-induced autoimmune haemolytic anaemia

Diagnosis drug-induced autoimmune haemolytic anaemia is diagnosed Women are 8.82% more likely than Men

152 537

Men receive the diagnosis drug-induced autoimmune haemolytic anaemia

4 524 (3.0 %)

Died from this diagnosis.

100
95
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80
75
70
65
60
55
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45
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15
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5
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182 044

Women receive the diagnosis drug-induced autoimmune haemolytic anaemia

6 544 (3.6 %)

Died from this diagnosis.

Risk Group for the Disease drug-induced autoimmune haemolytic anaemia - Men aged 0-5 and Women aged 75-79

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In Men diagnosis is most often set at age 0-94
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Less common in men the disease occurs at Age 95+in in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features drug-induced autoimmune haemolytic anaemia

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Absence or low individual and public risk
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Drug-induced autoimmune haemolytic anaemia - what does this mean

Drug-induced autoimmune haemolytic anaemia is a type of anaemia caused by an autoimmune reaction to certain drugs, resulting in the body's immune system attacking and destroying red blood cells. this can lead to a decrease in the number of red blood cells in the body, resulting in anaemia.

What happens during the disease - drug-induced autoimmune haemolytic anaemia

Drug-induced autoimmune haemolytic anaemia is a condition in which the body's immune system mistakenly attacks its own red blood cells, leading to a decrease in the number of red blood cells in circulation. this is caused by the drug causing the body to produce antibodies against the red blood cells, leading to the cells being destroyed. this can be due to a direct reaction to the drug or due to an antigen-antibody reaction. the result is a decrease in the number of red blood cells in the body, leading to anaemia.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Direct Coombs Test
  • Indirect Coombs Test
  • Antinuclear Antibody (ANA) Test
  • Serum Protein Electrophoresis (SPE)
  • Haptoglobin Test
  • Urine Analysis
  • Liver Function Tests (LFTs)
  • Kidney Function Tests (KFTs)
  • Drug Challenge Test
  • Bone Marrow Biopsy

Treatment and Medical Assistance

Main goal of the treatment: To reduce the destruction of red blood cells and improve the patient's overall health.
  • Prescribe medications to suppress the immune system and reduce the production of autoantibodies.
  • Administer corticosteroids and/or immunosuppressants to reduce inflammation and help the body to stop attacking its own red blood cells.
  • Provide supportive care such as transfusions and iron supplements to replenish the lost red blood cells.
  • Monitor the patient's blood count regularly and adjust medications accordingly.
  • Educate the patient about the disease and the importance of lifestyle changes such as avoiding triggers that may worsen symptoms.
  • Refer the patient to a hematologist or immunologist for further evaluation and treatment.
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17 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Drug-induced autoimmune haemolytic anaemia - Prevention

Drug-induced autoimmune haemolytic anaemia can be prevented by avoiding the use of drugs that can trigger the condition, such as certain antibiotics, anticonvulsants, and non-steroidal anti-inflammatory drugs. patients should also be monitored closely for any signs or symptoms of the disease, and if any are noticed, the drug should be stopped immediately and medical attention sought.