(D82) Immunodeficiency associated with other major defects

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57 978 in individuals diagnosis immunodeficiency associated with other major defects confirmed
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2 889 deaths with diagnosis immunodeficiency associated with other major defects
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5% mortality rate associated with the disease immunodeficiency associated with other major defects

Diagnosis immunodeficiency associated with other major defects is diagnosed Men are 15.88% more likely than Women

33 592

Men receive the diagnosis immunodeficiency associated with other major defects

1 730 (5.2 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
24 386

Women receive the diagnosis immunodeficiency associated with other major defects

1 159 (4.8 %)

Died from this diagnosis.

Risk Group for the Disease immunodeficiency associated with other major defects - Men and Women aged 5-9

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In Men diagnosis is most often set at age 0-19, 25-29, 40-44, 50-64, 70-84
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Less common in men the disease occurs at Age 20-24, 30-39, 45-49, 65-69, 85-95+Less common in women the disease occurs at Age 40-44, 50-69, 80-95+
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In Women diagnosis is most often set at age 0-39, 45-49, 70-79

Disease Features immunodeficiency associated with other major defects

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Absence or low individual and public risk
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Immunodeficiency associated with other major defects - what does this mean

Immunodeficiency associated with other major defects is a condition in which the immune system is unable to function properly due to a combination of genetic and environmental factors. this can lead to an increased susceptibility to infections, autoimmune diseases, and other health problems.

What happens during the disease - immunodeficiency associated with other major defects

Immunodeficiency associated with other major defects is a condition caused by a mutation in genes that control the development and function of the immune system. this can lead to a weakened immune system, making the individual more susceptible to infections and other diseases. this condition can also be caused by other factors such as certain medications, radiation, chemotherapy, or inherited disorders. in some cases, the underlying cause of the immunodeficiency is unknown.

Clinical Pattern

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How does a doctor diagnose

  • Complete blood count
  • Lymphocyte count
  • CD4/CD8 ratio
  • Immunoglobulin levels
  • Viral load tests
  • T-cell proliferation assay
  • Flow cytometry
  • Genetic testing
  • X-ray imaging
  • CT scan
  • MRI scan
  • Ultrasound
  • Endoscopy
  • Biopsy

Treatment and Medical Assistance

Main goal of the treatment: To strengthen the immune system and reduce the risk of infections.
  • Administering immunoglobulin injections
  • Administering antibiotics to prevent infections
  • Administering antifungal medications to prevent fungal infections
  • Administering antiviral medications to prevent viral infections
  • Providing nutritional support
  • Providing supportive care to reduce the risk of complications
  • Providing physical therapy to improve strength and mobility
  • Providing psychological support to reduce anxiety and depression
  • Providing education and counseling to the patient and family
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8 Days of Hospitalization Required
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55 Hours Required for Outpatient Treatment

Immunodeficiency associated with other major defects - Prevention

The best way to prevent immunodeficiency associated with other major defects is to ensure that the individual is receiving adequate nutrition, is up-to-date on their vaccinations, and is receiving regular medical check-ups. additionally, it is important to avoid any activities that may put the individual at risk for infections, such as contact with people who are ill, and to practice good hygiene.

Specified forms of the disease

(D82.0) Wiskott-Aldrich syndrome
(D82.1) Di George syndrome
(D82.2) Immunodeficiency with short-limbed stature
(D82.3) Immunodeficiency following hereditary defective response to Epstein-Barr virus
(D82.4) Hyperimmunoglobulin E [IgE] syndrome
(D82.8) Immunodeficiency associated with other specified major defects
(D82.9) Immunodeficiency associated with major defect, unspecified