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(D83) Common variable immunodeficiency
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174 785 in individuals diagnosis common variable immunodeficiency confirmed
3 186 deaths with diagnosis common variable immunodeficiency
2% mortality rate associated with the disease common variable immunodeficiency
Diagnosis common variable immunodeficiency is diagnosed Men are 19.46% more likely than Women
104 402
Men receive the diagnosis common variable immunodeficiency
1 828 (1.8 %)Died from this diagnosis.
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70 383
Women receive the diagnosis common variable immunodeficiency
1 358 (1.9 %)Died from this diagnosis.
Risk Group for the Disease common variable immunodeficiency - Men and Women aged 0-5
In Men diagnosis is most often set at age 0-64, 70-89
Less common in men the disease occurs at Age 65-69, 90-95+Less common in women the disease occurs at Age 80-89, 95+
In Women diagnosis is most often set at age 0-79, 90-94
Disease Features common variable immunodeficiency
Absence or low individual and public risk
Common variable immunodeficiency - what does this mean
Common variable immunodeficiency (cvid) is an immunodeficiency disorder characterized by a decrease in the production of antibodies against pathogens. it is caused by a defect in the development of b cells, which are responsible for producing antibodies. this defect leads to a decrease in the production of antibodies, resulting in an increased susceptibility to infections.
What happens during the disease - common variable immunodeficiency
Common variable immunodeficiency (cvid) is a primary immunodeficiency disorder caused by a defect in the development and/or function of b cells, which results in an inability to produce enough antibodies to fight off infection. this defect occurs due to a combination of genetic, environmental, and lifestyle factors, including mutations in genes associated with b cell maturation and signaling, exposure to certain environmental toxins, and lifestyle factors such as smoking or poor nutrition. this leads to an increased susceptibility to infections, and can also cause autoimmunity and other immune-related disorders.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete blood count (CBC)
- Lymphocyte subset analysis
- Flow cytometry
- Serum immunoglobulins evaluation
- Serum complement levels
- Antibody responses to vaccines
- Functional assays of T- and B-cell responses
- Genetic testing
Treatment and Medical Assistance
Main goal of the treatment: To restore and maintain immune system function.
- Identifying and avoiding potential infections and other environmental triggers.
- Antibiotic and antiviral medications to prevent and treat infections.
- Immunoglobulin replacement therapy to replace lost antibodies.
- Immunomodulatory therapy to boost immune system function.
- Stem cell transplantation to replace defective immune cells.
- Regular monitoring of blood and other laboratory tests.
10 Days of Hospitalization Required
126 Hours Required for Outpatient Treatment
Common variable immunodeficiency - Prevention
Common variable immunodeficiency can be prevented by maintaining a healthy lifestyle, including regular exercise, a balanced diet, and avoiding smoking and excessive alcohol intake. vaccination is also important for preventing other infections that could lead to the development of common variable immunodeficiency.