(N01.6) Rapidly progressive nephritic syndrome : dense deposit disease

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103 436 in individuals diagnosis rapidly progressive nephritic syndrome : dense deposit disease confirmed
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2 185 deaths with diagnosis rapidly progressive nephritic syndrome : dense deposit disease
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2% mortality rate associated with the disease rapidly progressive nephritic syndrome : dense deposit disease

Diagnosis rapidly progressive nephritic syndrome : dense deposit disease is diagnosed Women are 35.75% more likely than Men

33 231

Men receive the diagnosis rapidly progressive nephritic syndrome : dense deposit disease

937 (2.8 %)

Died from this diagnosis.

100
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70
65
60
55
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70 205

Women receive the diagnosis rapidly progressive nephritic syndrome : dense deposit disease

1 248 (1.8 %)

Died from this diagnosis.

Risk Group for the Disease rapidly progressive nephritic syndrome : dense deposit disease - Men aged 55-59 and Women aged 25-29

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In Men diagnosis is most often set at age 0-89
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Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 5-9, 90-95+
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In Women diagnosis is most often set at age 0-5, 10-89

Disease Features rapidly progressive nephritic syndrome : dense deposit disease

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Absence or low individual and public risk
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Rapidly progressive nephritic syndrome : dense deposit disease - what does this mean

Rapidly progressive nephritic syndrome (rpns) is a rare, progressive kidney disorder caused by dense deposit disease (ddd). it is characterized by the formation of dense deposits in the kidney glomeruli, which can lead to damage of the kidney cells, inflammation and scarring of the glomeruli, and ultimately kidney failure.

What happens during the disease - rapidly progressive nephritic syndrome : dense deposit disease

Rapidly progressive nephritic syndrome (rpns) is a rare type of glomerulonephritis characterized by the formation of dense deposits in the glomeruli. these deposits are composed of various proteins, including iga, c3, and c1q. the deposition of these proteins in the glomeruli leads to inflammation and scarring of the renal tissue, resulting in the impairment of the glomerular filtration rate and a decrease in the renal clearance of electrolytes and other substances. over time, this leads to a decline in renal function and the development of end-stage renal failure.

Clinical Pattern

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How does a doctor diagnose

  • Complete blood count
  • Urine analysis
  • Urine protein/creatinine ratio
  • Serum creatinine and urea levels
  • Serum electrolytes
  • Renal ultrasound
  • Renal biopsy
  • Serum complement levels
  • Serum antinuclear antibody test
  • Serum C3 and C4 levels

Treatment and Medical Assistance

Main goal of the treatment: To reduce the progression of the disease and improve the patient's quality of life.
  • Administering corticosteroids
  • Administering immunosuppressant drugs
  • Administering plasma exchange
  • Administering anti-inflammatory drugs
  • Performing kidney biopsy
  • Performing dialysis
  • Monitoring kidney function
  • Providing dietary guidance
  • Providing lifestyle advice
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11 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Rapidly progressive nephritic syndrome : dense deposit disease - Prevention

Rapidly progressive nephritic syndrome (rns) is a serious and potentially life-threatening disorder that can be prevented by early detection and aggressive treatment. early diagnosis and treatment with immunosuppressive drugs, such as corticosteroids and cytotoxic agents, can reduce the risk of progression to end-stage renal disease. additionally, lifestyle modifications, such as smoking cessation, regular exercise, and a healthy diet, can help reduce the risk of developing rns.