(P55) Haemolytic disease of fetus and newborn

More details coming soon

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747 925 in individuals diagnosis haemolytic disease of fetus and newborn confirmed
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1 731 deaths with diagnosis haemolytic disease of fetus and newborn

Diagnosis haemolytic disease of fetus and newborn is diagnosed Women are 3.07% more likely than Men

362 484

Men receive the diagnosis haemolytic disease of fetus and newborn

660 (0.2 %)

Died from this diagnosis.

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95
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385 441

Women receive the diagnosis haemolytic disease of fetus and newborn

1 071 (0.3 %)

Died from this diagnosis.

Risk Group for the Disease haemolytic disease of fetus and newborn - Men and Women aged 0

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In Men diagnosis is most often set at age 0-5
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Less common in men the disease occurs at Age 5-95+Less common in women the disease occurs at Age 0-95+
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In Women diagnosis is most often set at age 0-1

Disease Features haemolytic disease of fetus and newborn

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Absence or low individual and public risk
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Haemolytic disease of fetus and newborn - what does this mean

Haemolytic disease of the fetus and newborn is a condition caused by the mother's immune system producing antibodies that attack the baby's red blood cells, leading to anemia, jaundice, and in severe cases, death of the fetus or newborn. it is most commonly caused by rh incompatibility between the mother and baby, but can also be caused by other blood group incompatibilities.

What happens during the disease - haemolytic disease of fetus and newborn

Haemolytic disease of the fetus and newborn is caused by the presence of rh antigens on the surface of red blood cells in the fetus that are incompatible with the mother's rh antigens. this causes the mother's immune system to produce antibodies that attack the fetal red blood cells, leading to haemolysis and anaemia. this can cause complications such as hydrops fetalis, intrauterine growth restriction, and neonatal jaundice.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Fetal Ultrasound
  • Cord Blood Testing
  • Fetal Blood Sampling
  • Amniocentesis
  • Maternal Serum Screening
  • Newborn Screening
  • Genetic Testing

Treatment and Medical Assistance

Main Goal: Treating Haemolytic Disease of Fetus and Newborn
  • Administer Rh immune globulin to the mother
  • Perform exchange transfusions for the baby
  • Provide supportive care to the baby
  • Monitor the baby's hemoglobin levels
  • Administer antibiotics to prevent infection
  • Monitor the baby's bilirubin levels
  • Provide phototherapy to reduce bilirubin levels
  • Monitor the baby's liver function
  • Administer medications to reduce red blood cell destruction
  • Provide nutritional support to the baby
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11 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Haemolytic disease of fetus and newborn - Prevention

The best way to prevent haemolytic disease of the fetus and newborn (hdfn) is for pregnant women to receive rh immunoglobulin (rhig) at 28 weeks of gestation and again within 72 hours after delivery. rhig prevents the mother from forming antibodies against her fetus's red blood cells, which can lead to hdfn. additionally, it is important for pregnant women to be tested for their rh factor early in pregnancy and to receive antenatal care throughout.

Specified forms of the disease

(P55.0) Rh isoimmunization of fetus and newborn
(P55.1) ABO isoimmunization of fetus and newborn
(P55.8) Other haemolytic diseases of fetus and newborn
(P55.9) Haemolytic disease of fetus and newborn, unspecified