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Men receive the diagnosis osteoporosis, unspecified
4 858 (3.0 %)Died from this diagnosis.
Women receive the diagnosis osteoporosis, unspecified
33 042 (1.6 %)Died from this diagnosis.
Единый механизм развития остеопороза отсутствует, поскольку динамика изменения строения и состава костной ткани определяется провоцирующим заболеванием (при вторичном остеопорозе) и наличием различных факторов риска (при первичном процессе). При этом выделяют ряд последовательных стадий, которые наблюдаются при всех видах патологии.
Формирование костной ткани нарушается во время роста либо в процессе обновления. Разрушение кости начинает преобладать над ее восстановлением. Плотность, масса кости снижаются. Уменьшается толщина кортикального слоя, количество трабекул. В результате при остеопорозе страдают прочностные характеристики кости, у детей возникают деформации, у взрослых – переломы.
Риск возникновения переломов увеличивается пропорционально снижению плотности костной ткани. При снижении плотности костей на 10% частота переломов возрастает в 2-3 раза. Остеопороз в первую очередь поражает кости с преобладанием губчатого вещества (позвонки, кости предплечья в области лучезапястного сустава), поэтому типичными осложнениями заболевания являются переломы тел позвонков, дистального эпифиза лучевой кости.
(Diminished hunger, Loss of appetite, Lack of appetite, Decreased hunger, Reduced appetite, Anorexia, Poor appetite, Decreased intake, Lack of interest in food)
Decreased appetite is a symptom that can manifest in a variety of ways. It can manifest as a lack of interest in food, difficulty eating, or a lack of hunger. This symptom can develop gradually over time or suddenly. It can be caused by a variety of medical conditions, medications, or psychological ...
(Back pain, Dorsalgia, Lumbago, Sciatica, Thoracic pain, Lumbar strain, Spinal pain, Sacroiliac pain, Muscle spasm, Osteoarthritis pain)
Backache is a common symptom of musculoskeletal pain, usually felt as an ache or stiffness in the lower back. It can develop gradually or suddenly, and can range from mild to severe. Common causes of backache include poor posture, muscular strain, injury, or overuse. Symptoms can include pain in the...
(Aches, Agony, Distress, Misery, Soreness, Suffering, Torture, Torment, Agonizing, Tenderness, Throbbing, Sharpness, Stabbing, Pricking, Twinge, Throb, Pang)
Bone pain is a dull, deep, aching sensation that is felt in the bones or joints. It can range from mild to severe, and can be a constant or an intermittent ache. It can develop suddenly or gradually, and can be localized to one area or widespread throughout the body. It can manifest as a sharp, stab...
(Unintended weight loss, Unexplained weight loss, Rapid weight loss, Excessive weight loss, Drastic weight loss, Sudden weight loss, Substantial weight loss, Significant weight loss, Unwanted weight loss, Unexpected weight loss)
Abnormal weight loss is a symptom of an underlying medical condition. It is characterized by a significant decrease in body weight that is not related to changes in diet or exercise habits. It may be accompanied by fatigue, decreased appetite, nausea, and other symptoms. It can develop gradually or ...
(Lumbar pain, Backache, Lumbago, Lumbar ache, Back discomfort, Lower backache, Lower back discomfort, Lumbar discomfort, Lower back pain, Lumbar agony)
Lower back pain is characterized by aching or stiffness in the lower back, often radiating down the legs. It can develop suddenly or gradually, and can range in intensity from mild to severe. It can be caused by a number of factors, including injury, overuse, poor posture, obesity, or disease. Its m...
(Ache in the spine, Spinal discomfort, Spinal soreness, Spinal tenderness, Spinal agony, Spinal ache, Spinal pain, Spinal distress, Spinal hurt, Spinal uneasiness)
Pain in the spine is a common symptom that can present in various ways. It may start as a dull ache in the lower back that gradually worsens over time. It can be localized to one area or radiate to other parts of the body. It can be a shooting, stabbing, or burning sensation. It can be aggravated by...