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(T57.2) Toxic effect: manganese and its compounds
More details coming soon
39 865 in individuals diagnosis toxic effect: manganese and its compounds confirmed
Diagnosis toxic effect: manganese and its compounds is diagnosed Men are 9.36% more likely than Women
21 798
Men receive the diagnosis toxic effect: manganese and its compounds
0 (less than 0.1%)Died from this diagnosis.
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18 067
Women receive the diagnosis toxic effect: manganese and its compounds
0 (less than 0.1%)Died from this diagnosis.
Risk Group for the Disease toxic effect: manganese and its compounds - Men and Women aged 0-5
In Men diagnosis is most often set at age 0-74, 80-84, 90-94
Less common in men the disease occurs at Age 75-79, 85-89, 95+Less common in women the disease occurs at Age 70-79, 85-95+
In Women diagnosis is most often set at age 0-69, 80-84
Disease Features toxic effect: manganese and its compounds
Absence or low individual and public risk
Toxic effect: manganese and its compounds - what does this mean
Manganese toxicity occurs when an individual is exposed to excessive amounts of manganese and its compounds, either through inhalation, ingestion, or skin contact. high levels of manganese in the body can lead to neurological symptoms such as difficulty walking, tremors, and difficulty speaking. long-term exposure can lead to permanent neurological damage.
What happens during the disease - toxic effect: manganese and its compounds
Toxic effect of manganese and its compounds is the result of its accumulation in the body, leading to a range of neurological symptoms. the mechanism of action is thought to be related to manganese's ability to interfere with the function of various enzymes, proteins and neurotransmitters. this can lead to increased oxidative stress, mitochondrial dysfunction, and excitotoxicity, ultimately leading to a range of neurological symptoms.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Blood tests to measure manganese levels
- Urine tests to measure manganese levels
- Imaging tests such as X-rays, CT scans, and MRI scans to check for manganese deposits in the body
- Lung function tests to check for respiratory problems caused by manganese exposure
- Neurological tests to check for cognitive and motor problems caused by manganese exposure
- Skin tests to check for skin irritation caused by manganese exposure
- Hearing tests to check for hearing loss caused by manganese exposure
Treatment and Medical Assistance
Main goal: To reduce the toxic effects of manganese and its compounds
- Eliminate sources of manganese exposure
- Provide supportive care, such as oxygen, intravenous fluids, and medications to reduce nausea and vomiting
- Administer chelating agents to help remove manganese from the body
- Perform dialysis to help remove manganese from the body
- Provide nutritional support
- Provide physical and occupational therapy to help with any physical or cognitive impairments
- Provide psychological support to help with any emotional or psychological issues
4 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Toxic effect: manganese and its compounds - Prevention
The best way to prevent toxic effects from manganese and its compounds is to reduce exposure to them by wearing protective clothing and using respiratory protection when handling these materials, as well as avoiding contact with them as much as possible. additionally, good ventilation and engineering controls should be employed in any work environment where manganese and its compounds are present.